Interactions between Germ Cells and Extracellular Matrix Glycoproteins during Migration and Gonad Assembly in the Mouse Embryo [PDF]
, 1997 Cells are known to bind to individual extracellular matrix glycoproteins in a complex and poorly understood way. Overall strength of adhesion is thought to be mediated by a combinatorial mechanism, involving adhesion of a cell to a variety of binding ...
Alvarez-Buylla +22 more
core +5 more sources
Endogenous laminin is required for human airway smooth muscle cell maturation
Respiratory Research, 2006 Background Airway smooth muscle (ASM) contraction underlies acute bronchospasm in asthma. ASM cells can switch between a synthetic-proliferative phenotype and a contractile phenotype.
Tran Thai +4 more
doaj +1 more source
Patterned and Functionalized Nanofiber Scaffolds in Three-Dimensional Hydrogel Constructs Enhance Neurite Outgrowth and Directional Control [PDF]
J Neural Eng. 2014 Dec;11(6):066009, 2015 Neural tissue engineering holds incredible potential to restore functional capabilities to damaged neural tissue. It was hypothesized that patterned and functionalized nanofiber scaffolds could control neurite direction and enhance neurite outgrowth. Aligned nanofibers were created according to a mathematical model and were shown to enable significant ...
arxiv +1 more source
Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation. [PDF]
, 1991 The integrin alpha 6 beta 1 is a prominent laminin receptor used by many cell types. In the present work, we isolate clones and determine the primary sequence of the chick integrin alpha 6 subunit.
de Curtis, I +3 more
core +3 more sources
A Family of Laminin α2 Chain-Deficient Mouse Mutants: Advancing the Research on LAMA2-CMD
Frontiers in Molecular Neuroscience, 2020 The research on laminin α2 chain-deficient congenital muscular dystrophy (LAMA2-CMD) advanced rapidly in the last few decades, largely due to availability of good mouse models for the disease and a strong interest in preclinical studies from scientists ...
Kinga I. Gawlik, Madeleine Durbeej
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 BackgroundDespite the advancements in microsurgical techniques and noteworthy research in the last decade, peripheral nerve lesions have still weak functional outcomes in current clinical practice.
Martino Guiotto +6 more
doaj +1 more source
Cumulative prognostic power of laminin genes in colorectal cancer
BMC Medical Genomics, 2018 Background Laminins are a major family of extracellular matrix proteins and the main component of basement membranes. Laminins are involved in many if not all stages of cancer progression, and expression of laminin genes has prognostic value in various ...
Vladimir V. Galatenko +4 more
doaj +1 more source
Impairment Mechanisms and Intervention Approaches for Aged Human Neuromuscular Junctions
Frontiers in Molecular Neuroscience, 2020 The neuromuscular junction (NMJ) is a chemical synapse formed between a presynaptic motor neuron and a postsynaptic muscle cell. NMJs in most vertebrate species share many essential features; however, some differences distinguish human NMJs from others ...
Yomna Badawi +2 more
doaj +1 more source
Frontiers in Oncology, 2022 Laminin is an extracellular matrix multidomain trimeric glycoprotein, that has a potential role in tumor progression. Here, we studied the effects of non-small cell lung cancer (NSCLC) cells interaction on laminin and explored the underlying mechanism of
Xiaopeng Zhao +6 more
doaj +1 more source
The immunohistochemical analysis of fibronectin, collagen type III, laminin, and cytokeratin 5 in putrified skin [PDF]
, 1993 Fibronectin, collagen type III, laminin, and cytokeratin 5 were visualized in normal skin and in skin showing early or advanced signs of autolytic decomposition to prove whether the immunohistochemical analysis of these antigens can provide useful ...
Betz, P. +5 more
core +1 more source