Results 41 to 50 of about 174,268 (199)

Avian neural crest cell attachment to laminin: involvement of divalent cation dependent and independent integrins [PDF]

, 1991
The mechanisms of neural crest cell interaction with laminin were explored using a quantitative cell attachment assay. With increasing substratum concentrations, an increasing percentage of neural crest cells adhere to laminin.
Bronner-Fraser, Marianne, Lallier, Thomas   +1 more
core  

Overexpression of LAMC2 predicts poor prognosis in colorectal cancer patients and promotes cancer cell proliferation, migration, and invasion

Tumor Biology, 2017
Laminin γ2 (LAMC2) has been reported to be involved in the development and progression of a variety of tumors. However, its function in human colorectal cancer is unclear. Our study aimed to investigate the role of laminin γ2 in colorectal cancer.
Dandan Huang, Changzheng Du, Dengbo Ji, Jianzhong Xi, Jin Gu   +4 more
doaj   +1 more source

Effects of Trans-Cinnamaldehyde on Reperfused Ischemic Skeletal Muscle and the Relationship to Laminin

Journal of Investigative Surgery, 2021
Purpose Ischemia-reperfusion (I-R) injury is a serious problem caused by vascular trauma, tourniquet use and/or compartment syndrome. Studies have reported that skeletal muscle function is impaired due to the lower extremity I-R injury.
Esra Pekoglu, Belgin Buyukakilli, Cagatay Han Turkseven, Ebru Balli, Gulsen Bayrak, Burak Cimen, Senay Balci   +6 more
doaj   +1 more source

Attenuation of serum laminin concentrations upon treatment of chronic hepatitis [PDF]

, 2009
Objectives: The aim of this work was to determine the serum laminin level cutoff point for predicting liver fibrosis highlighting its diagnostic value and determining the effect of treatment on serum laminin concentrations.
Agcheli, K., Estakhri, R., Kashifard, M., Majidi, G., Nouri, M., Parsian, H., Qujeq, D., Rahimipour, A., Soumi, M.H.   +8 more
core  

Prenatal muscle development in a mouse model for the secondary dystroglycanopathies [PDF]

, 2016
The defective glycosylation of α-dystroglycan is associated with a group of muscular dystrophies that are collectively referred to as the secondary dystroglycanopathies.
A Leschziner, A Matsakas, A Yoshida, AM Beedle, AR Raphael, B Xia, B-V BD de, C Godfrey, C Longman, C Whitmore, CA Schneider, D Merrick, D Montarras, DE Michele, DJ Blake, DJ Lefeber, E Hohenester, E Stevens, F Muntoni, H Yin, J Reeuwijk van, J Ross, JB Miller, K Buysse, K Kobayashi, KM Wright, KP Campbell, L Wells, M Brockington, M Brockington, M Kanagawa, M Kanagawa, M Narusawa, M Ontell, MD Henry, MJ Duxson, MM Goddeeris, MR Ackroyd, MR Ackroyd, O Armand, S Chan, S Cirak, S Costanzo Di, S Sato, S Schiaffino, S Sugita, SC Brown, T Roscioli, T Willer, TJ Hawke   +49 more
core   +1 more source

Autoimmunity against laminin 332

Frontiers in Immunology, 2023
Laminin 332 is a heterotrimeric structural protein of the basal membrane zone (BMZ) of the skin and adjacent mucosal tissues. The importance of laminin 332 for the structural integrity of the BMZ is demonstrated by mutations in any of the three genes ...
Sabrina Patzelt, Enno Schmidt, Enno Schmidt   +2 more
doaj   +1 more source

Differentiation of neural-type cells on multi-scale ordered collagen-silica bionanocomposites [PDF]

Biomaterials Science, Royal Society of Chemistry (RSC), 2020, 2020
Cells respond to biophysical and biochemical signals. We developed a composite filament from collagen and silica particles modified to interact with collagen and/or present a laminin epitope (IKVAV) crucial for cell-matrix adhesion and signal transduction.
arxiv  

Native chick laminin-4 containing the beta 2 chain (s-laminin) promotes motor axon growth. [PDF]

, 1996
After denervation of muscle, motor axons reinnervate original synaptic sites. A recombinant fragment of the synapse specific laminin beta 2 chain (s-laminin) was reported to inhibit motor axon growth.
Brandenberger, R, Chiquet, M, Engel, J, Kammerer, RA   +3 more
core   +1 more source

Binding properties of Treponema denticola lipooligosaccharide

Journal of Oral Microbiology, 2013
Background and objective: The cell-surface lipooligosaccharide (LOS) of Treponema denticola possesses several biological properties. The aim of this study was to investigate the binding properties of T.
Daniel Grenier
doaj   +1 more source

Selection and Characterization of an α6β4 Integrin blocking DNA Aptamer

Molecular Therapy: Nucleic Acids, 2016
The heterodimeric laminin receptor α6β4 integrin plays a central role in the promotion of tumor cell growth, invasion, and organotropic metastasis. As an overproduction of the integrin is often linked to a poor prognosis, the inhibition of integrin α6β4 ...
Katharina Berg, Tobias Lange, Florian Mittelberger, Udo Schumacher, Ulrich Hahn   +4 more
doaj   +1 more source