Results 41 to 50 of about 221,211 (337)

Nerve Fiber Immunohistochemical Panel Discriminates between Nerve Sheath and Perivascular Wall Tumors

open access: yesVeterinary Sciences, 2022
Benign and malignant nerve sheath tumors (NST) pose a major challenge in routine diagnostic anatomic pathology because of shared histomorphological features with other soft-tissue tumors (STT).
Sílvia Sisó   +5 more
doaj   +1 more source

Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity

open access: yesNature Communications, 2014
Blood brain barrier (BBB) breakdown is not only a consequence of but also contributes to many neurological disorders, including stroke and Alzheimer’s disease.
Yao Yao   +3 more
semanticscholar   +1 more source

A monoclonal antibody that blocks the activity of a neurite regeneration-promoting factor: studies on the binding site and its localization in vivo [PDF]

open access: yes, 1986
Work from several laboratories has identified a proteoglycan complex secreted by a variety of non-neuronal cells that can promote neurite regeneration when applied to the surface of culture dishes.
Chiu, Arlene Y.   +2 more
core   +1 more source

Endothelial Basement Membrane Laminin 511 Contributes to Endothelial Junctional Tightness and Thereby Inhibits Leukocyte Transmigration

open access: yesCell Reports, 2017
Endothelial basement membranes constitute barriers to extravasating leukocytes during inflammation, a process where laminin isoforms define sites of leukocyte exit; however, how this occurs is poorly understood.
Jian Song   +16 more
doaj   +1 more source

Vascular Endothelial Growth Factor (VEGF) Prevents the Downregulation of the Cholinergic Phenotype in Axotomized Motoneurons of the Adult Rat [PDF]

open access: yes, 2018
Vascular endothelial growth factor (VEGF) was initially characterized by its activity on the vascular system. However, there is growing evidence indicating that VEGF also acts as a neuroprotective factor, and that its administration to neurons suffering ...
Acosta, Lourdes   +4 more
core   +1 more source

Anti-laminin-1 Autoantibodies, Pregnancy Loss and Endometriosis

open access: yesClinical and Developmental Immunology, 2004
Laminin-1 is a major component and multifunctional glycoprotein of basement membranes that consists of three different subunits, α1, β1 and γ1 chains. It is the earliest synthesized network-forming protein during embryogenesis and
Junko Inagaki   +4 more
doaj   +1 more source

Specific decellularized extracellular matrix promotes the plasticity of human ocular surface epithelial cells

open access: yesFrontiers in Medicine, 2022
The ocular surface is composed of two phenotypically and functionally different epithelial cell types: corneal and the conjunctival epithelium. Upon injury or disease, ocular surface homeostasis is impaired resulting in migration of conjunctival ...
Tiago Ramos   +14 more
doaj   +1 more source

Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment

open access: yesNature Communications, 2014
Lack of robust methods for establishment and expansion of pluripotent human embryonic stem (hES) cells still hampers development of cell therapy. Laminins (LN) are a family of highly cell-type specific basement membrane proteins important for cell ...
S. Rodin   +21 more
semanticscholar   +1 more source

Artificial restoration of the linkage between laminin and dystroglycan ameliorates the disease progression of MDC1A muscular dystrophy at all stages [PDF]

open access: yes, 2005
Laminin-α2 deficient congenital muscular dystrophy, classified as MDC1A, is a severe progressive muscle-wasting disease that leads to death in early childhood.
Meinen, Sarina
core   +1 more source

A Family of Laminin α2 Chain-Deficient Mouse Mutants: Advancing the Research on LAMA2-CMD

open access: yesFrontiers in Molecular Neuroscience, 2020
The research on laminin α2 chain-deficient congenital muscular dystrophy (LAMA2-CMD) advanced rapidly in the last few decades, largely due to availability of good mouse models for the disease and a strong interest in preclinical studies from scientists ...
Kinga I. Gawlik, Madeleine Durbeej
doaj   +1 more source

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