Comparison of Two Diagnostic Assays for Anti-Laminin 332 Mucous Membrane Pemphigoid [PDF]
Anti-laminin 332 mucous membrane pemphigoid (MMP) is an autoimmune blistering disease characterized by predominant mucosal lesions and autoantibodies against laminin 332.
Stephanie Goletz +10 more
doaj +5 more sources
Molecular diagnosis of anti-laminin 332 (epiligrin) mucous membrane pemphigoid [PDF]
Background Mucous membrane pemphigoid is a group of chronic subepithelial autoimmune blistering diseases that mainly affect mucous membranes. Laminin 332-specific autoantibodies are present in approximately 1/3 of the patients, being associated with an ...
Roxana Chiorean +9 more
doaj +3 more sources
Autoimmunity against laminin 332 [PDF]
Laminin 332 is a heterotrimeric structural protein of the basal membrane zone (BMZ) of the skin and adjacent mucosal tissues. The importance of laminin 332 for the structural integrity of the BMZ is demonstrated by mutations in any of the three genes ...
Sabrina Patzelt +2 more
doaj +2 more sources
Subunit-Specific Reactivity of Autoantibodies Against Laminin-332 Reveals Direct Inflammatory Mechanisms on Keratinocytes [PDF]
Laminin-332 pemphigoid is a rare and severe autoimmune blistering disease, caused by IgG autoantibodies targeting laminin-332 in the dermal-epidermal basement zone.
Lei Bao +13 more
doaj +2 more sources
Gene Expression in Amnion-Derived Cells Cultured on Recombinant Laminin 332—A Preliminary Study [PDF]
Human amniotic cells (hAC) exhibit characteristics of undifferentiated cells and immunomodulatory properties. Recognition of the relationship between amniotic cells and components of the extracellular matrix is an important condition for their ex vivo ...
Katarzyna Skowron-Kandzia +5 more
doaj +2 more sources
Anti-Laminin 332-Type Mucous Membrane Pemphigoid [PDF]
Anti-laminin (LM) 332-type mucous membrane pemphigoid (MMP) is a rare autoimmune bullous disease and was originally discovered as anti-epiligrin cicatricial pemphigoid.
Luhuai Shi, Xiaoguang Li, Hua Qian
doaj +2 more sources
Case report: A case of anti-laminin 332 mucous membrane pemphigoid associated with severe pharyngolaryngeal involvement [PDF]
A 74-year-old woman presented with a 30-day history of blisters and erosions in the oral cavity, trunk, and left eye conjunctival mucosa, also reporting a weight loss of 15 kg in the last 3 months.
Eleonora Quattri +9 more
doaj +2 more sources
A Case of IgG and IgA Anti-Laminin-332 Antibody-Positive Mucous Membrane Pemphigoid with IgG and IgA Anti-Envoplakin and Anti-Periplakin Antibodies [PDF]
A 76-year-old Japanese man presented with a 6-year history of a sore throat. He was treated at several clinics without any improvement before being referred to us. Physical examination revealed widespread erosions and ulcers from the palate to the larynx.
Yoshiaki Matsushima +12 more
doaj +2 more sources
Laminin 332 functionalized surface improve implant roughness and oral keratinocyte bioactivity [PDF]
Objective: The biological seal (BS) at the implant-tissue interface is essential for the success of dental implants (DIs), and the absence of a proper BS can lead to peri-implantitis.
Sandra J. Perdomo +2 more
doaj +2 more sources
A Probing of the Issue of Detecting IgG, IgG4 and IgA Antibodies to Laminin 332 Epitopes in Mucous Membrane Pemphigoid: A Clinical-Laboratory Experience of a Single Central European University Dermatology Department [PDF]
Justyna Gornowicz-Porowska,1 Magdalena Jałowska,2 Agnieszka Seraszek-Jaros,3 Monika Bowszyc-Dmochowska,4 Elżbieta Kaczmarek,3 Marian Dmochowski2 1Department and Division of Practical Cosmetology and Skin Diseases Prophylaxis, Poznan ...
Gornowicz-Porowska J +5 more
doaj +2 more sources

