Results 31 to 40 of about 125,741 (149)

Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages [PDF]

, 2007
Mutations in laminin-alpha2 cause a severe congenital muscular dystrophy, called MDC1A. The two main receptors that interact with laminin-alpha2 are dystroglycan and alpha7beta1 integrin.
Ruegg, M. A., Patrizia Barzaghi, Lochmuller, H., Sarina Meinen, Markus A. Ruegg, Lin, S., Hanns Lochmüller, Shuo Lin, Barzaghi, P., Meinen, S.   +9 more
core   +1 more source

Anti-laminin 332 mucous membrane pemphigoid in a young woman treated with rituximab [PDF]

, 2022
Mucous membrane pemphigoid, formerly known as cicatricial pemphigoid, is a rare and difficult-to-treat bullous disorder that occurs most commonly in older adults.
Braunlich, Katherine, Bisbee, Elizabeth, Porta, Adriana Della, Gitin, Alexander, Motaparthi, Kiran   +4 more
core   +1 more source

Agrin binds to the nerve-muscle basal lamina via laminin. [PDF]

, 1997
Agrin is a heparan sulfate proteoglycan that is required for the formation and maintenance of neuromuscular junctions. During development, agrin is secreted from motor neurons to trigger the local aggregation of acetylcholine receptors (AChRs) and other ...
Brandenberger, R, Ralph Brandenberger, Matthias Gesemann, Gesemann, M., Denzer, A. J., Chiquet, M, Ruegg, M. A., Denzer, A J, Brandenberger, R., Markus A. Ruegg, Matthias Chiquet, Gesemann, M, Ruegg, M A, Chiquet, M., Alain J. Denzer   +14 more
core   +1 more source

Efficacy of intradermal allogeneic fibroblast injections in junctional epidermolysis bullosa

Russian Open Medical Journal, 2022
Objective — to assess the efficacy and safety of intradermal injections of allogeneic fibroblasts into non-healing wounds in a patient with junctional epidermolysis bullosa.
Alexey A. Kubanov, Arfenya E. Karamova, Vadim V. Chikin, Ekaterina S. Monchakovskaya, Mariya A. Nefedova   +4 more
doaj   +1 more source

Laminin 332: A New Hope as a Prognostic Marker in Triple Negative Breast Carcinomas [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Laminin expression is supposed to be associated with a number of invasive carcinomas, particularly squamous cell carcinoma of the oral cavity and uterine cervix.
Gayatri Rath, Sushanta Kumar Singh, Ashok Kumar Panda   +2 more
doaj   +1 more source

Artificial restoration of the linkage between laminin and dystroglycan ameliorates the disease progression of MDC1A muscular dystrophy at all stages [PDF]

, 2005
Laminin-α2 deficient congenital muscular dystrophy, classified as MDC1A, is a severe progressive muscle-wasting disease that leads to death in early childhood.
Meinen, Sarina
core   +1 more source

Table_1_Comparison of Two Diagnostic Assays for Anti-Laminin 332 Mucous Membrane Pemphigoid.docx

, 2021
Anti-laminin 332 mucous membrane pemphigoid (MMP) is an autoimmune blistering disease characterized by predominant mucosal lesions and autoantibodies against laminin 332.
Maike M. Holtsche (10827686), Takashi Hashimoto (127174), Hendri H. Pas (7848348), Miranda Nijenhuis (11755781), Barbara Horvath (11755784), Stephanie Goletz (11755778), Enno Schmidt (314592), Federica Giurdanella (5133869), Gilles F. H. Diercks (5133872), Detlef Zillikens (314591)   +9 more
core   +1 more source

DataSheet_1_Subunit-Specific Reactivity of Autoantibodies Against Laminin-332 Reveals Direct Inflammatory Mechanisms on Keratinocytes.docx

, 2021
Laminin-332 pemphigoid is a rare and severe autoimmune blistering disease, caused by IgG autoantibodies targeting laminin-332 in the dermal-epidermal basement zone.
Takashi Hashimoto (127174), Xiaoguang Li (148206), Lei Bao (9883), Jing Li (10611), Payal M. Patel (11753045), Hua Qian (2534959), Farzan Solimani (6865541), Michael Hertl (504182), Kyle T. Amber (9340504), Norito Ishii (3140550), Dario Didona (6865547)   +10 more
core   +1 more source

Table_2_Subunit-Specific Reactivity of Autoantibodies Against Laminin-332 Reveals Direct Inflammatory Mechanisms on Keratinocytes.xlsx

, 2021
Laminin-332 pemphigoid is a rare and severe autoimmune blistering disease, caused by IgG autoantibodies targeting laminin-332 in the dermal-epidermal basement zone.
Takashi Hashimoto (127174), Xiaoguang Li (148206), Lei Bao (9883), Jing Li (10611), Payal M. Patel (11753045), Hua Qian (2534959), Farzan Solimani (6865541), Michael Hertl (504182), Kyle T. Amber (9340504), Norito Ishii (3140550), Dario Didona (6865547)   +10 more
core   +1 more source

Selection and Characterization of an α6β4 Integrin blocking DNA Aptamer

Molecular Therapy: Nucleic Acids, 2016
The heterodimeric laminin receptor α6β4 integrin plays a central role in the promotion of tumor cell growth, invasion, and organotropic metastasis. As an overproduction of the integrin is often linked to a poor prognosis, the inhibition of integrin α6β4 ...
Katharina Berg, Tobias Lange, Florian Mittelberger, Udo Schumacher, Ulrich Hahn   +4 more
doaj   +1 more source