Results 51 to 60 of about 125,741 (149)
Indian Journal of Paediatric Dermatology, 2020 Epidermolysis bullosa (EB) comprises a group of genetically determined skin fragility disorders, characterized by blistering of the skin and mucosae following mechanical trauma, which includes four major forms (EB simplex, junctional EB [JEB], dystrophic
Ankita Choudhary +3 more
doaj +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Journal of Periodontal Research, EarlyView.Sixty years after the introduction of dental implants, it is clear that soft‐tissue integration is as essential as osseointegration. This review outlines how peri‐implant soft tissues develop, protect, and sometimes fail, revealing key knowledge gaps and new opportunities to improve long‐term implant stability.
Fabiana Aellos +6 more
wiley +1 more source
, 2014 (A) (1w) After 1 week, laminin-332 was expressed in the BM of the new epithelium and in the FC, but not in the epithelial layer facing the implant. After 2 weeks, laminin-332 was intensely expressed in the CT, and the innermost cells of the PIE facing ...
Ryosuke Kondo (540341) +7 more
core +1 more source
Symmetrical Skin Lesions on the Gluteal Region in a Patient with Anti-Laminin-332 Mucous Membrane Pemphigoid [PDF]
, 2021 Mucous membrane pemphigoid (MMP), previously called cicatricial pemphigoid, is a rare subepidermal immunobullous disorder that primarily affects the mucous membranes (1,2). MMP is divided into two major subtypes, anti-BP180-type MMP and anti-laminin-332 (
Maki, Nobuki +8 more
core +2 more sources
Biomarker Research, 2017 Background Monomeric laminin-γ2 in urine is a potential biomarker for bladder cancer. However, the current detection system uses an antibody that cannot discriminate between monomeric laminin-γ2 and the heterotrimeric γ2 chain of laminin-332, which may ...
Masatoshi Nakagawa +9 more
doaj +1 more source
Gentamicin induces LAMB3 nonsense mutation readthrough and restores functional laminin 332 in junctional epidermolysis bullosa. [PDF]
Proc Natl Acad Sci U S A, 2018 Herlitz junctional epidermolysis bullosa (H-JEB) is an incurable, devastating, and mostly fatal inherited skin disease for which there is only supportive care.
Lincoln V +10 more
europepmc +2 more sources
Increased Genetic Instability in Exfoliated Oral Cells in Patients With Epidermolysis Bullosa
Oral Diseases, EarlyView.ABSTRACT Objective To analyze the nuclear abnormalities of cytotoxicity—karyorrhexis (KR), karyolysis (KL), and pyknosis (PN)—and genotoxicity—micronucleus (MN) in exfoliated cells from different sites of the oral mucosa in patients with Epidermolysis Bullosa (EB) and a control group.
Ana Carolina Sias Franco Franzosi +5 more
wiley +1 more source
Inside the function of the 67 kDa laminin receptor (67LR): a new promising target for cancer drug discovery by structure-based virtual screening [PDF]
, 2010 The 67 kDa laminin receptor (67LR) is a non-integrin cell-surface receptor for the extracellular matrix derived from the dimerization of a 37 kDa cytosolic precursor (37LRP).
Pesapane, Ada
core +1 more source
Experimental Physiology, EarlyView.Abstract Fibroblast growth factor 23 (FGF23) is closely associated with atrial fibrillation (AF), yet whether it modulates sodium and calcium currents in atrial myocytes remains unclear. ETV1, a key transcription factor regulating atrial electrical conduction, might also be involved in FGF23‐mediated AF.
Qiaoting Yu +7 more
wiley +1 more source