Results 141 to 150 of about 18,044 (328)

Identification of an interchromosomal compartment by polymerization of nuclear-targeted vimentin [PDF]

open access: yes, 1998
A number of structural and functional subnuclear compartments have been described, including regions exclusive of chromosomes previously hypothesized to form a reactive nuclear space.
Bridger, JM   +3 more
core  

Strange Laminates

open access: yesMathematical Methods in the Applied Sciences, 2012
Laminates made of composite anisotropic layers have a large varieties of different possible elastic responses. Still remaining in the classical field of linear elasticity, it is possible to obtain, with laminates, elastic behaviors that are very strange and completely unusual not only for classical materials, like metallic alloys, but also for the same
openaire   +2 more sources

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

open access: yesExploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao   +15 more
wiley   +1 more source

Sheet lamination

open access: yes, 2022
The sheet lamination (SHL) is one of the processes in additive technologies. In the past, it has been used extensively to make fast, inexpensive paper prototypes. Then the application expanded to metals, polymers (only thermoplastics), textiles and ceramics, which also required the improvement of procedures, i.e. devices (3D printers).
openaire   +2 more sources

Mutations in GFAP Alter Early Lineage Commitment of Organoids

open access: yesGlia, EarlyView.
Mutations in GFAP alter lineage commitment of organoids. The severity of this commitment defect is dependent on the method of embryoid body formation. GFAP is expressed in iPSCs and during early stages of organoid development. Graphical abstract was created with BioRender.com .
Werner Dykstra   +14 more
wiley   +1 more source

Hypothalamic Astrocytes Exhibit Glycolytic Features Making Them Prone for Glucose Sensing

open access: yesGlia, EarlyView.
Hypothalamic astrocytes versus cortical astrocytes: are more glycolytic due to high Pkm2, Glut1 and Mct4 expression do not exhibit glutamate‐induced glycolysis detect glucose concentration variations via an AMPK sensor with altered lactate production. ABSTRACT In the hypothalamus, detection of energy substrates such as glucose is essential to regulate ...
Sarah Geller   +11 more
wiley   +1 more source

The Extremely Low Mechanical Force Generated by Nano‐Pulling Induces Global Changes in the Microtubule Network, Nuclear Morphology, and Chromatin Transcription in Neurons

open access: yesSmall, EarlyView.
Nano‐pulling induces stabilization, reorganization, and reorientation of the microtubule network. The nucleus of stretched cells experiences increased lateral tension, becomes more spherical, and develops surface grooves. At the level of gene expression regulation, changes in nuclear morphology induce global chromatin remodeling, leading to reduced ...
Alessandro Falconieri   +7 more
wiley   +1 more source

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