Results 221 to 230 of about 18,044 (328)

Ultrastructure of the Endoplasmic Reticulum in Eukaryotic Microalgae

Journal of Eukaryotic Microbiology, Volume 72, Issue 5, September/October 2025.
ABSTRACT The endoplasmic reticulum (ER) is a large and highly dynamic component of the eukaryotic endomembrane system. In eukaryotic microalgae, it plays six distinct roles: (1) It envelopes the chromatin to form the nucleus. (2) It forms cisternae in the cytoplasm, some of which scaffold the synthesis of proteins destined for incorporation into ...
Ursula Goodenough, Robyn Roth
wiley   +1 more source

Divergent Contribution of Cytoplasmic Actins to Nuclear Structure of Lung Cancer Cells. [PDF]

Int J Mol Sci
Shagieva G, Dugina V, Burakov A, Levuschkina Y, Kudlay D, Boichuk S, Khromova N, Vasileva M, Kopnin P.   +8 more
europepmc   +1 more source

Lamin A/C gene: sex-determined expression of mutations in Dunnigan-type familial partial lipodystrophy and absence of coding mutations in congenital and acquired generalized lipoatrophy.

, 2000
Corinne Vigouroux, Jocelyne Magré, Marie‐Christine Vantyghem, Charlotte Bourut, Olivier Lascols, Sue Shackleton, David J. Lloyd, Bruno Guerci, Giuseppa Padova, P. Valensi, André Grimaldi, R. Piquemal, Philippe Touraine, Richard C. Trembath, Jacqueline Capeau   +14 more
openalex   +1 more source

Both emerin and lamin C depend on lamin A for localization at the nuclear envelope [PDF]

, 2001
O. Anthony Vaughan, Mauricio Alvarez-Reyes, Joanna M. Bridger, Jos L. V. Broers, Frans C.�S. Ramaekers, Manfred Wehnert, Glen E. Morris, William G. F. Whitfield, Christopher J. Hutchison   +8 more
openalex   +1 more source

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Advanced Science, Volume 12, Issue 29, August 7, 2025.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei, Yuhua Zhang, Wei Cao, Nan Cheng, Yun Xiao, Yongjun Zhu, Yan Xu, Lei Zhang, Lingna Guo, Jun Song, Su‐hua Sha, Buwei Shao, Fang Ma, Jingwen Yang, Zheng Ying, Zuhong He, Renjie Chai, Qiaojun Fang, Jianming Yang   +18 more
wiley   +1 more source

At the nucleus of cancer: how the nuclear envelope controls tumor progression. [PDF]

MedComm (2020)
Paganelli F, Poli A, Truocchio S, Martelli AM, Palumbo C, Lattanzi G, Chiarini F.   +6 more
europepmc   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, Volume 12, Issue 29, August 7, 2025.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Nuclear warfare: pathogen manipulation of the nuclear pore complex and nuclear functions. [PDF]

mBio
Steiert B, Weber MM.
europepmc   +1 more source

Involvement of the Lamin Rod Domain in Heterotypic Lamin Interactions Important for Nuclear Organization [PDF]

, 2001
Eric C. Schirmer, Tinglu Guan, Larry Gerace   +2 more
openalex   +1 more source

LIMK1 as a Novel Kinase of β‐Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5

Advanced Science, Volume 12, Issue 29, August 7, 2025.
Li et al. innovatively map the kinase‐substrate network in esophageal cancer metastasis. Their study demonstrates that LIM domain kinase 1 (LIMK1) and Cyclin‐dependent kinase 5 (CDK5) synergistically increase the phosphorylation of β‐catenin, thereby activating the Wnt/β‐catenin signaling pathway to promote esophageal cancer metastasis.
Shu‐Jun Li, Zhuo‐Ran Liang, Zhi‐Chao Liu, Xue‐Ping Luo, Jun‐Yi Li, Xiao‐Mei Yu, Xuan‐Zhang Huang, Yan He, Tao‐Yang Xu, Jiao‐Jiao Xu, Shao‐Cong Peng, Yu‐Xiang Song, Yan He, Xiao‐Wan Zhuang, Can‐Can Zheng, Fan Zhang, Alfred King‐Yin Lam, Wei Dai, Ming‐Liang He, Bo Liu, Qi Zhao, Guo‐Liang Lu, Jin‐Bao Liu, Zhen‐Ning Wang, Zhi‐Gang Li, Ze‐Xian Liu, Wen‐Wen Xu, Bin Li   +27 more
wiley   +1 more source