Results 251 to 260 of about 18,044 (328)

Multiomics Profiling of Extracellular Vesicles Supports Their Involvement in Endothelial Senescence‐Associated Vascular Dysfunction

Journal of Extracellular Biology, Volume 4, Issue 8, August 2025.
Proteomic and miRNAseq analyses of exosomes derived from early passage (non‐senescent) versus senescent human coronary artery endothelial cells derived from the same donor indicate that senescence changed the protein and miRNA content of shed exosomes towards a more pro‐inflammatory profile.
Ryan E. Hogans, Yun Lin, Gabriela Grigorean, Ana Cristina Grodzki, Rachel R. Mizenko, Anne Knowlton, Randy P. Carney, Angie Gelli, Pamela J. Lein   +8 more
wiley   +1 more source

Interplay Between the Cytoskeleton and DNA Damage Response in Cancer Progression. [PDF]

Cancers (Basel)
Halim CE, Deng S, Crasta KC, Yap CT.
europepmc   +1 more source

Developmental regulation of linkers of the nucleoskeleton to the cytoskeleton during mouse postnatal retinogenesis [PDF]

, 2013
Hodzic, Didier, Kolb, Thorsten, Razafsky, David S, Ward, Candace L   +3 more
core   +2 more sources

Extracellular Matrix Signaling Cues: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 8, August 2025.
Targeting ECM dysregulation: therapeutic strategies for disease intervention. Dysregulated ECM composition and biomechanics contribute to disease pathogenesis in cancer and fibrotic disorders. Physical modulation: Nanomedicine‐based strategies tune ECM physical properties (e.g., density, stiffness) to enhance drug penetration and therapeutic efficacy ...
Tian Zhao, Ye Huang, Jingfei Zhu, Yujie Qin, Hao Wu, Jiaxuan Yu, Qianwen Zhai, Shun Li, Xiang Qin, Dengfeng Wang, Tingting Li, Yiyao Liu   +11 more
wiley   +1 more source

Mouse polyomavirus infection induces lamin reorganisation. [PDF]

FEBS J
Bruštíková K, Ryabchenko B, Žáčková S, Šroller V, Forstová J, Horníková L.   +5 more
europepmc   +1 more source

Optimizing Proximity Proteomics on the EvoSep‐timsTOF LC–MS System

PROTEOMICS, Volume 25, Issue 15, Page 58-71, August 2025.
ABSTRACT Proximity‐dependent biotinylation (BioID) is a powerful means of exploring the cellular environments in which proteins reside. Expressing a protein of interest (bait) fused to a biotin ligase and adding biotin induces the covalent biotinylation of proximal partners (preys), which are recovered on streptavidin beads and identified by MS ...
Julia Kitaygorodsky, Brendon Seale, Vesal Kasmaeifar, Reuben Samson, Zhen‐Yuan Lin, Martina Tersigni, Saya Sedighi, Cassandra J. Wong, Anne‐Claude Gingras   +8 more
wiley   +1 more source

How the Oocyte Nucleolus Is Turned into a Karyosphere: The Role of Heterochromatin and Structural Proteins. [PDF]

J Dev Biol
Nikolova V, Markova M, Zhivkova R, Chakarova I, Hadzhinesheva V, Delimitreva S.   +5 more
europepmc   +1 more source

Loss of A-type lamins and genomic instability [PDF]

, 2009
Gonzalez-Suarez, Ignacio, Gonzalo, Susana, Redwood, Abena B   +2 more
core   +2 more sources

ZNF224 enhances the oncogenic function of p21 via p53 and AKT pathways in melanoma

The FEBS Journal, Volume 292, Issue 15, Page 3986-4005, August 2025.
KRAB zinc finger protein ZNF224 acts as an oncogenic factor in melanoma cells, enhancing p21 cytosolic retention and impairing nuclear p21 cytostatic activity through stimulation of the AKT pathway. Furthermore, ZNF224 regulates transcriptional expression levels of p21 via p53.
Leandra Sepe, Umberto Candia, Dario Sasso del Verme, Elvira Toscano, Marianna Toriello, Gaetano Sodaro, Roberta Rapuano, Simona Romano, Michela Grosso, Giovanni Paolella, Angelo Lupo, Paola Costanzo, Elena Cesaro   +12 more
wiley   +1 more source

The Basis of Diversity in Laminopathy Phenotypes Caused by Variants in the Intron 8 Donor Splice Site of the <i>LMNA</i> Gene. [PDF]

Int J Mol Sci
Shchagina O, Gilazova L, Filatova A, Vafina Z, Murtazina A, Chigvintceva P, Kudryashova O, Polyakov A, Kutsev S, Bulakh M, Skoblov M.   +10 more
europepmc   +1 more source