Cancer-associated SPOP mutations enlarge nuclear size and facilitate nuclear envelope rupture upon farnesyltransferase inhibitor treatment. [PDF]
Wang Z+14 more
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Sensing the squeeze: nuclear mechanotransduction in health and disease. [PDF]
Srivastava LK, Ehrlicher AJ.
europepmc +1 more source
DNA damage causes ATM-dependent heterochromatin loss leading to nuclear softening, blebbing, and rupture. [PDF]
Eskndir N+8 more
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From gene to mechanics: a comprehensive insight into the mechanobiology of LMNA mutations in cardiomyopathy. [PDF]
Veltrop RJA+7 more
europepmc +1 more source
Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism. [PDF]
Pujadas Liwag EM+16 more
europepmc +1 more source
Pulsus alternans under left ventricular assist device in a patient with dilated cardiomyopathy and LMNA mutation. [PDF]
Sakai R, Kashimura T, Inomata T.
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The molecular basis of lamin-specific chromatin interactions
Wang B+10 more
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Decreased DNA density is a better indicator of a nuclear bleb than lamin B loss.
Bunner S+26 more
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Much has been written on laminitis and its treatment over the past 200 years. This article makes a brief review of the practical essentials of the disease and considers some of the recent trends in therapy. Knowledge of the pathogenesis and aetiology of equine laminitis is still very incomplete but recent work in the United States by Coffman and his ...
LB Jeffcott, CM Colles
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Laminating the hippocampus [PDF]
Lamination of neurons and fibre projections is a fundamental organizational principle of the mammalian cerebral cortex. A laminated organization is likely to be essential for cortical function, as studies in mutant mice have revealed causal relationships between lamination defects and functional deficits.
Förster, Eckart+2 more
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