Results 131 to 140 of about 3,501,652 (356)

Bipolarity and Ambivalence in Landscape Architecture [PDF]

open access: yes, 2010
Our discipline of landscape architecture contains bipolarity, not only in terms of landscape and architecture but also because the idea of landscape is both aesthetic and scientific.
Koh, J.
core   +1 more source

Landscape of Microsatellite Instability Across 39 Cancer Types.

open access: yesJCO Precision Oncology, 2017
Purpose Microsatellite instability (MSI) is a pattern of hypermutation that occurs at genomic microsatellites and is caused by defects in the mismatch repair system. Mismatch repair deficiency that leads to MSI has been well described in several types of
Russell Bonneville   +8 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Predicting evolution and visualizing high-dimensional fitness landscapes [PDF]

open access: yesarXiv, 2013
The tempo and mode of an adaptive process is strongly determined by the structure of the fitness landscape that underlies it. In order to be able to predict evolutionary outcomes (even on the short term), we must know more about the nature of realistic fitness landscapes than we do today. For example, in order to know whether evolution is predominantly
arxiv  

Пейзаж в творчестве Леонарда Туржанского

open access: yesИскусство Евразии, 2017
Леонард (Леонид) Викторович Туржанский (1875-1945) – один из интереснейших русских художников начала XX века. Его небольшие работы, написанные непосредственно с натуры, отличаются точной и тонкой передачей определенного конкретного состояния природы. Они
Филиппова, О.Н.
doaj   +1 more source

Landscape History and Theory: from Subject Matter to Analytic Tool [PDF]

open access: yes, 2004
This essay explores how landscape history can engage methodologically with the adjacent disciplines of art history and visual/cultural studies.
Birksted, Jan Kenneth
core  

A Barren Landscape?

open access: yes, 2004
We consider the generation of a non-perturbative superpotential in F-theory compactifications with flux. We derive a necessary condition for the generation of such a superpotential in F-theory.
A. Giryavets   +9 more
core   +3 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Метафизика природы: искусствоведческий анализ Т. Буркхардта китайской пейзажной живописи

open access: yesИскусство Евразии, 2017
Статья посвящена наследию еще недостаточно известного в России  философа, культуролога, искусствоведа Титуса Буркхардта. Дается обзор раздела одной из его ведущих работ «Сакральное искусство Востока и Запада.
Фотиева, И.В.   +1 more
doaj   +1 more source

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