Results 181 to 190 of about 1,387,202 (292)

GENOMICS AND PUBLIC HEALTH: LEGAL AND SOCIO-ETHICAL PERSPECTIVES

, 2007
Acknowledgements -- Pt. I. Population screening: issues, realities and possibilities -- A Introduction: expansion of screening / J. Gerard Loeber -- Expansion of newborn screening: current achievements and new prospects / Bridget Wilcken ...
Knoppers, Bartha Maria, ed.
core  

Fine-Scale Landscape Genomics Show Asymmetric Patterns of Gene Flow for the Invasive Mosquito <i>Aedes albopictus</i>. [PDF]

Ecol Evol
Ding JY, Reed EMX, Reiskind MH, Burford Reiskind MO.   +3 more
europepmc   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

Integrating landscape genomics and machine learning to analyze the genetic structure and specific molecular markers of Chinese dairy goats (Capra hircus). [PDF]

J Anim Sci Biotechnol
Xiong J, Shang M, Bao J, Liu T, Yang P, Sun X, Jiang Y, Zhang L.   +7 more
europepmc   +1 more source

Testing least cost path (LCP) models for travel time and kilocalorie expenditure: Implications for landscape genomics. [PDF]

PLoS One, 2020
Gowen KM, de Smet TS.
europepmc   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Population and landscape genomics provide insights into the adaptive genetic variation and future climate-induced vulnerability of the endangered tree species <i>Phoebe bournei</i>. [PDF]

Hortic Res
Zhang J, Liu Y, Hu X, Wang L, Fu N, Ma X, Ma W, Zhang Y, Han X, Yang Q, Tong Z.   +10 more
europepmc   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

Lithobiomes Heterogeneity and Geographic Distance Shape the Landscape Genomics Within Brazilian Mountain Systems. [PDF]

Ecol Evol
Cabrini M, Trovó M, Takahashi D, Suyama Y, Ramos R, Lira C.   +5 more
europepmc   +1 more source

Knowledge status and sampling strategies to maximize cost-benefit ratio of studies in landscape genomics of wild plants. [PDF]

Sci Rep, 2020
Santos AS, Gaiotto FA.
europepmc   +1 more source