Results 61 to 70 of about 439,531 (308)

xCell: Digitally portraying the tissue cellular heterogeneity landscape [PDF]

Genome Biology, 2017
AbstractTissues are complex milieu consisting of numerous cell-types. Numerous recent methods attempt to enumerate cell subsets from transcriptomes. However, available method used limited source for training and displayed only partial portrayal of the full cellular landscape.
Aran, Dvir, Hu, Zicheng, Butte, Atul J.
openaire   +5 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A Landscape-Clustering Zoning Strategy to Map Multi-Crops in Fragmented Cropland Regions Using Sentinel-2 and Sentinel-1 Imagery with Feature Selection

Agriculture
Crop mapping using remote sensing is a reliable and efficient approach to obtaining timely and accurate crop information. Previous studies predominantly focused on large-scale regions characterized by simple cropping structures.
Guanru Fang, Chen Wang, Taifeng Dong, Ziming Wang, Cheng Cai, Jiaqi Chen, Mengyu Liu, Huanxue Zhang   +7 more
doaj   +1 more source

Habitat structure: a fundamental concept and framework for urban soil ecology [PDF]

, 2007
Habitat structure is defined as the composition and arrangement of physical matter at a location. Although habitat structure is the physical template underlying ecological patterns and processes, the concept is relatively unappreciated and underdeveloped
BC Scharenbroch, BE Wolfe, C Kremen, C Milesi, CA Martin, D Hope, D Hope, DA Wardle, DM Green, DT Bolger, E Shochat, E Shochat, EC Mueller, ED McCoy, ED McCoy, EJ Rebek, GA Langellotto, GG Whitney, GW Korthals, H Gibb, J Tews, JI Nassauer, JL Avondet, JM Grove, JP Kaye, JP Kaye, JP Kaye, K Lorenz, K Thompson, LA Baker, LB Byrne, LB Byrne, LB Byrne, Loren B. Byrne, M Alberti, M Guerra, MA Pavao-Zuckerman, MJ McDonnell, MM Carreiro, MW Beck, NB Grimm, NE Golubiewski, NE McIntyre, NL Law, PJ Craul, PM Groffman, PM Shrewsbury, R Geiger, R Pouyat, RD Bornstein, RS Ostfeld, SB Celestian, SH Faeth, SH Faeth, SK Bramen, SS Bell, STA Pickett, T Miyashita, T Montague, TP Nuhn, VT Eviner, W Zhu, Y Natuhara   +62 more
core   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Genetic structure of wild rice Zizania latifolia in an expansive heterogeneous landscape along a latitudinal gradient

Frontiers in Ecology and Evolution, 2022
Global aquatic habitats are undergoing rapid degradation and fragmentation as a result of climate change and changes in land use. Understanding the genetic variability and adaptive potential of aquatic plant species is thus important for conservation ...
Godfrey Kinyori Wagutu, Godfrey Kinyori Wagutu, Godfrey Kinyori Wagutu, Xiangrong Fan, Xiangrong Fan, Xiangrong Fan, Wenlong Fu, Wenlong Fu, Miriam Chepkwemoi Tengwer, Miriam Chepkwemoi Tengwer, Miriam Chepkwemoi Tengwer, Wei Li, Yuanyuan Chen   +12 more
doaj   +1 more source

Déterminants de l'hétérogénéité temporelle et spatiale de la pression de foreurs de tige sur maïs dans une région agricole du Kenya [PDF]

, 2011
This study is integrated in a context of research on ecosystem services on pest regulation. In the context of high population rural area in mid altitude Kenya, smallholders have diversified production systems and intensification is based on labor.
Harignordoquy, Miren
core  

Integrating the landscape epidemiology and genetics of RNA viruses: rabies in domestic dogs as a model [PDF]

, 2012
Landscape epidemiology and landscape genetics combine advances in molecular techniques, spatial analyses and epidemiological models to generate a more real-world understanding of infectious disease dynamics and provide powerful new tools for the study of
Anderson, Cross, Cullingham, D. L. HORTON, Dietzschold, Eng, K. BRUNKER, K. HAMPSON, Knobel, McCallum, R. BIEK, Sharma, Swanepoel, Wandeler, Weiss, Windiyaningsih, Zanoni   +16 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Analysis of the heterogeneity of urban expansion landscape patterns and driving factors based on a combined Multi-Order Adjacency Index and Geodetector model

Ecological Indicators, 2022
Under conditions of rapid urbanization, quantitative measurement of the expansion characteristics of urban landscapes and evaluation of their spatial and temporal differentiation properties is an important scientific problem.
Jing Liu, Quanli Xu, Junhua Yi, Xin Huang   +3 more
doaj   +1 more source