Results 71 to 80 of about 439,531 (308)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Seasonality buffers carbon budget variability across heterogeneous landscapes in Alaskan Arctic tundra

open access: yesEnvironmental Research Letters, 2021
Arctic tundra exhibits large landscape heterogeneity in microtopography, hydrology, and active layer depth. While many carbon flux measurements and experiments are done at or below the mesoscale (⩽1 km), modern ecosystem carbon modeling is often done at ...
Josh Hashemi   +4 more
doaj   +1 more source

Scratching the Surface and Digging Deeper: Exploring Ecological Theories in Urban Soils [PDF]

open access: yes, 2009
Humans have altered the Earth more extensively during the past 50 years than at any other time in history (Millennium Assessment 2003). A significant part of this global change is the conversion of land covers from native ecosystems to those dominated by
Byrne, Loren B   +1 more
core   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Time-dependent optical linewidth in fluctuating environments: Stochastic models

open access: yes, 2001
Time-resolved optical lineshapes are calculated using a second-order inhomogeneous cumulant expansion. The calculation shows that in the inhomogeneous limit the optical spectra are determined solely by two-time correlation functions.
Diezemann, Gregor
core   +2 more sources

Spatial Control of Rabies on Heterogeneous Landscapes

open access: yesPLoS ONE, 2006
Rabies control in terrestrial wildlife reservoirs relies heavily on an oral rabies vaccine (ORV). In addition to direct ORV delivery to protect wildlife in natural habitats, vaccine corridors have been constructed to control the spread; these corridors are often developed around natural barriers, such as rivers, to enhance the effectiveness of vaccine ...
Colin A Russell   +2 more
openaire   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Bee diversity responses to forest and open areas in heterogeneous Atlantic Forest

open access: yesSociobiology, 2018
Agriculture driven landscape changes has caused worldwide forest loss and fragmentation, seriously affecting biodiversity and ecosystem services, amongst which pollination is remarkably important.
Laura Silva Nery   +5 more
doaj   +1 more source

Effects of Aphid Density and Plant Taxa on Predatory Ladybeetle Abundance at Field and Landscape Scales

open access: yesInsects, 2020
In agroecosystems, predatory ladybeetles play an important role in restraining aphid population growth and suppressing aphid populations. They can adapt to various habitats and make use of various aphid species associated with multiple host plants during
Hongsheng Pan   +7 more
doaj   +1 more source

A remote sensing based approach for optimizing sampling strategies in tree monitoring and agroforestry systems mapping [PDF]

open access: yes, 2019
Characterizing agroforestry systems (AFS) at landscape scale is of a great importance for development planning at regional scale in Africa. Therefore, the major constraint to effective AFS mapping with remote sensing is the high diversity within ...
Diouf, Abdoul Aziz   +4 more
core  

Home - About - Disclaimer - Privacy