Results 91 to 100 of about 338,455 (295)
Analysis of urban sprawl at mega city Cairo, Egypt using multisensoral remote sensing data, landscape metrics and gradient analysis [PDF]
, 2009 This paper is intended to highlight the capabilities of synergistic usage of remote sensing, landscape metrics and gradient analysis. We aim to improve the understanding of spatial characteristics and effects of urbanization on city level ...
Dech, Stefan +4 more
core
Measuring fragmentation of open space in urbanised Flanders: an evaluation of four methods [PDF]
, 2016 The open space in Flanders, the northern part of Belgium, can hardly be seen as really open. From the Middle Ages onward this area has been known for its spread out development pattern, which has even strengthened in recent decades.
Tempels, Barbara, Verbeek, Thomas
core +4 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Tropical Forest Landscape Fragmentation in Batang Toru Watershed, North Sumatra
Jurnal Manajemen Hutan Tropika, 2014 Timber-based forest management is now shifting to as broader scope including ecosystem-based management. Timber-oriented forest management frequently affects the fragmentation of forest landscape.
Samsuri Samsuri +3 more
doaj +3 more sources
Analysis of land use and land cover using ecological landscape metrics (case study: Arasbaran region) [PDF]
علوم محیطی, 2018 Introduction: A landscape is a heterogeneous and vast region consisting of a set of patches, habitats, and repetitive environmental elements. In recent studies, various metrics have been used to investigate the structure, function, and landscape pattern ...
Vahid Nasiri, Ali Asghar Darvishsefat
doaj
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Geometric approaches to computing 3D-landscape metrics
Landscape Online, 2010 The relationships between patterns and processes lie at the core of modern landscape ecology. These dependences can be quantified by using indices related to the patch-corridor-matrix model.
Mihai Sorin Stupariu +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source