Results 91 to 100 of about 87,651 (259)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Using landscape metrics to analyse urban spatial patterns in the Metropolitan area of Granada

open access: yesAnales de Geografía de la Universidad Complutense, 2010
Landscape metrics have been widely used to perform analyses of landscape structure, function and change. Within the last years, these metrics have been recently used to analyse urban landscapes.
Francisco Aguilera Benavente
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Multidimensional Assessment of the Aesthetic Quality of Natural Landscapes in Mount Wuyi National Park, China

open access: yesLand
Natural landscapes are scenic complexes accessible to the public within national parks. Exploring their aesthetic quality can promote an emotional connection between the public and the landscape, which has a positive significance in enhancing human well ...
Xin Zheng, Zhaoping Yang, Yayan Lu
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Relationship Between Aggregation Index and Change in the Values of Some Landscape Metrics as a Function of Cell Neighborhood Choice

open access: yesISPRS International Journal of Geo-Information
Landscape metrics are one of the main tools for studying changes in the landscape and the ecological structure of the territory. However, the calculation of some metrics yields significantly different values depending on the configuration of the “Cell ...
Paolo Zatelli   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Multiscale impacts of landscape metrics on water quality based on fine-grained land use maps

open access: yesFrontiers in Environmental Science
Quantifying the impact of landscape metrics on water quality can offer scientific supports for water conservation and land use planning. However, previous studies mainly relied on coarse land use maps, and were lack of understanding of effects from ...
Ya’nan Zhou   +11 more
doaj   +1 more source

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