Results 81 to 90 of about 99,404 (300)
iForest - Biogeosciences and Forestry, 2016 Landscape fragmentation is one of the main threats to South American temperate forests due to population growth, conversion of native forests to plantations of exotic species and non-sustainable timber harvesting.
Molina Juan R +4 more
doaj +1 more source
Drivers and Metrics for Quantifying IT Landscape Complexity
Mastering complexity is an important topic within the field of Enterprise Architecture (EA), and many companies perceive this as a difficult endeavour due to the growth and perpetual evolution of the Information Technology (IT) landscape. Numerous EA frameworks and methods exist that describe what an IT landscape is.
Eva Stoica +3 more
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Ecological IndicatorsLandscape metrics are significant indicators of ecological functions. However, limited data are available regarding the relationship between landscape metrics and soil ecological functions.
Chenhui Wei +5 more
doaj +1 more source
Landscape Online, 2008 Topography and relief variability play a key role in ecosystem functioning and structuring. However, the most commonly used concept to relate pattern to process in landscape ecology, the so-called patch-corridor-matrix model, perceives the landscape as a
Sebastian Hoechstetter +3 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Landscape metrics as a tool for evaluating scenarios for flood prevention and nature conservation
, 2011 Within the framework of the project "Flood Prevention and Nature Conservation in the Weisseritz area" ("HochNatur"), a method including landscape metrics was developed and applied to assess and to compare different land use scenarios with regard to flood
Hermann Heilmeier +4 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source