Results 101 to 110 of about 99,404 (300)
How to calculate landscape metrics for local landscapes?
, 2020 In the last few weeks, I was asked a similar question several times - how to calculate landscape metrics for local landscapes? In other words, how to divide the categorical input map into a number of smaller areas, and next calculate selected landscape metrics for each of the areas. Those areas have many names, such as tiles, squares, or motifels.
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Effects of Deforestation over the Cerrado Landscape: A Study in the Bahia Frontier
, 2021 The losses in the Brazilian Cerrado raise the need to understand the border regions between human activities and Cerrado remnants. This work aims to answer the questions: How does the landscape change in a deforestation area in the Brazilian Cerrado, and
Maria Isabel Sobral Escada +2 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
tool to calculate landscape metrics
, 2019 Quantifying landscape characteristics and linking them to ecological processes is one of the central goals of landscape ecology. Landscape metrics are a widely used tool for the analysis of patch-based, discrete land-cover classes.
Maximilian H. K. Hesselbarth +9 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Landscape metrics description.
, 2019 Landscape metrics description.
Katrin M. Meyer (7439123) +4 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
How do Changes in Land Use Patterns Affect Species Diversity? an Approach for Optimizing Landscape Configuration [PDF]
Heterogeneity of agricultural landscapes is supposed to be of significant importance for species diversity in agroecosystems (Weibull et al. 2003). Thus it is necessary to account for structural aspects of landscapes in land management decision processes.
Ralf Seppelt +2 more
core
The third dimension in landscape metrics analysis applied to Central Alentejo-Portugal [PDF]
, 2010 Landscape metrics have been widely developed over the last two decades, although the question remains: How does landscape metrics relates with ecological processes?
Carvalho, Luisa +2 more
core