Results 61 to 70 of about 2,063,143 (381)

Monotonicity of Fitness Landscapes and Mutation Rate Control [PDF]

, 2016
A common view in evolutionary biology is that mutation rates are minimised. However, studies in combinatorial optimisation and search have shown a clear advantage of using variable mutation rates as a control parameter to optimise the performance of ...
A Kong, AE Eiben, AE Nix, AF Agrawal, AF Agrawal, Alastair Channon, BMR Stadler, CA Aktipis, CA Aktipis, CG Knight, Christopher G. Knight, DR Rokyta, Elizabeth Aston, FC Adams, G Badis, HA Orr, HA Orr, HA Orr, HA Orr, HA Orr, I Bjedov, ID Falco, J Cervantes, J He, JA Visser de, JM Smith, John Aston, L Hadany, M Kimura, MJ McDonald, O Tenaillon, P Schuster, R Ahlswede, R Kassen, R Krašovec, R Poli, RA Fisher, RC MacLean, RJ Woods, Rok Krašovec, Roman V. Belavkin, RS Galhardo, S Banach, S Böttcher, S Collins, S Mazurkiewicz, SJ Freeland, T Bataillon, T Jansen, V Mustonen, WH Zhong, Y Ram   +51 more
core   +4 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Mainstreaming agrobiodiversity in planet-friendly school meals for children: a scoping review

The Lancet Planetary Health
Summary: The global shift away from healthy, diverse, and sustainable diets threatens children’s health and futures. Although school gardens and home-grown school feeding can reconnect children with nutritious, sustainably produced food, these ...
Natalia Estrada-Carmona, PhD, Maaike MA van Houtert, MSc, Silvia Araujo de Lima, MA, Paul Fauchon, MSc, Danny Hunter, PhD, Sarah K Jones, PhD, Ian Ondo, MSc, Piedad Pareja Cabrejos, MSc, Silvia Pastorino, PhD, Samuel Pironon, PhD, Meghajit Shijagurumayum, PhD, Mulele Sibeso, MSc, Samrat Singh, PhD, Roseline Remans, PhD   +13 more
doaj   +1 more source

Towards Resilient Regions: Policy Recommendations for Stimulating Synergy between Tourism and Landscape

Land, 2020
To make regions more resilient, a useful idea is that of synergy between tourism and landscape (i.e., a win-win situation). To help policymakers manage for synergy, we provide practical recommendations.
Jasper Heslinga, Peter Groote, Frank Vanclay   +2 more
doaj   +1 more source

The rethinking and enhancement of the natural and cultural heritage of the cultural landscapes: the case of Sečovlje and Janubio saltpans [PDF]

, 2019
Cultural landscapes represent a complex category where the nature-culture dichotomy seem to not be able to unfold the main features and the profound relations that humans have with the environment.
Abad Espinoza, Luis Gregorio
core   +6 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Identifying critical incentives for scaling out the adoption of agroecological practices–a systematic review of Peruvian cacao value chains

International Journal of Agricultural Sustainability
The growing global importance of agroecology highlights the pivotal role public and private sectors play in providing incentives and investments to catalyze behavioural changes and transform food systems.
Jonathan Mockshell, Godfrey Omulo, Collins Asante-Addo, Thea Nielsen Ritter, Marcela Quintero, Roseline Remans   +5 more
doaj   +1 more source

Migration, Continuity and Creativity in the Tropics

eTropic: electronic journal of studies in the tropics, 2013
Tropical Australia is a multicultural mosaic fashioned by various waves of migration and ancient Indigenous cultures. Migration, cultural diversity and multiculturalism have been at the heart of nation building in Australia. Tropical Australia represents
Hurriyet Babacan, Alperhan Babacan
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Robotic 3DCP fabrication of custom-fit slabs for irregular pontoons

Architectural Intelligence
This paper presents a case study on the use of 3D concrete printing (3DCP) to qualify rocky pontoons with spaces for recreational use—namely sitting areas, circulation trails and fishing spots—and biodiversity protection—providing habitat and refuge for ...
João Ribeiro, António Morais, João Miguel Silva, Filipe J. S. Brandão, Bruno Figueiredo, Paulo J. S. Cruz   +5 more
doaj   +1 more source