Results 81 to 90 of about 211,324 (292)

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

open access: yesAdvanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim   +12 more
wiley   +1 more source

Plantation forests and biodiversity conservation [PDF]

open access: yes, 2003
There are five key reasons why biodiversity conservation should be considered a part of plantation management. (1) The plantation estate is large, and balancing various land management values with wood and pulp production is important when extensive ...
Hobbs, R.J., Lindenmayer, D.B., Salt, D.
core   +2 more sources

Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells

open access: yesAdvanced Science, EarlyView.
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale   +6 more
wiley   +1 more source

Exploring the restorativeness of different hydrodynamic landscapes in world natural heritage sites

open access: yesFrontiers in Child and Adolescent Psychiatry
Audiovisual environmental perception has been the focus of numerous empirical studies. This study employs virtual reality (VR) to explore how different hydrodynamic waterscapes in Jiuzhaigou World Natural Heritage Site affect physiological and ...
Ping Zhang   +16 more
doaj   +1 more source

Sustainable development and conservation of biological heritage in Australia and New Zealand [PDF]

open access: yes, 1999
The aim of this paper is to encourage greater attention by planners to conservation of native or indigenous biodiversity. It explains what is meant by indigenous, or native, biodiversity and why indigenous biodiversity conservation must become an on ...
Jay, Grace Mairi M.
core   +1 more source

Landscape metrics and indices : an overview of their use in landscape research [PDF]

open access: yes, 2009
The aim of this overview paper is to analyze the use of various landscape metrics and landscape indices for the characterization of landscape structure and various processes at both landscape and ecosystem level.
Antrop, Marc   +4 more
core   +2 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Charting the Future of Conservation in Arizona: Innovative Strategies for Preserving Its Natural Resources

open access: yesConservation
The article explores future directions toward the conservation of the state of Arizona, aiming to preserve its multiple natural resources, including landscapes, wildlife, flora, unique ecosystems, and water resources. We evaluate the current governmental
Matteo Bodini
doaj   +1 more source

BioCultural Landscapes per la rigenerazione innovativa dei territori di montagna [PDF]

open access: yes, 2016
Simplification of agricultural systems, farmland abandonment, uncontrolled urbanization, together with global scale drivers, determine fast and unpredictable phenomena of hydrogeological instability, biodiversity decline and identity loss.
BAIAMONTE, Giuseppe   +3 more
core  

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

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