Results 121 to 130 of about 270,632 (283)

Optimizing speed change lane lengths for two-way ten-lane expressways: a VISSIM and SSAM simulation-based approach

Scientific Reports
With rapid economic development, expressway traffic volumes have surged, resulting in severe congestion. To address this, expanding expressways to two-way ten-lane configurations has become a primary strategy for alleviating traffic pressure.
Dan Xiong, Quan Yu, Huihui Guo
doaj   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Decision Making Improvement Based on the Ahead Traffic Flow During the Lane Change Manoeuvre Via Model Predictive Control

IET Intelligent Transport Systems
This paper proposes a novel decision‐making framework that combines the influence of ahead traffic flow with the driver's personal decisions, thereby addressing the impact of transient traffic flow on lane‐change decision‐making.
Mohsen Rafat, Shahram Azadi, Mozhgan Faramarzi, Ali Analooee   +3 more
doaj   +1 more source

A review of vehicle lane change decisions in human–machine mixed driving environments

Digital Transportation and Safety
With the development of autonomous driving technology, the human–machine mixed driving environment has become the predominant form of future road traffic.
Zheng Huang, Hua Fang, Yongliang Lin, Xinyue Hu   +3 more
doaj   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Stability analysis for heterogeneous traffic flow with lane-change disturbance

Transport
Stability analysis and benefit estimation have substantial implications for lane-change decision-making to reduce delay and variation. Connected platoons drive with minor headway to increase capacity, whereas dividing or reforming platoons significantly
Hao Li, Yun Pu, Lingjuan Chen, Xiaoyu Luo   +3 more
doaj   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

Deep learning-based lane change trajectory prediction

For fully automated driving vehicles, lane change is one of the most common and important driving scenarios, and there are many accidents caused by lane change. For a vehicle in motion, if it cannot intelligently respond to its surrounding vehicle’s lane
Xu, Fengchen
core  

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Analysis of lane change crashes [PDF]

HS319/S3059This report defines the problem of lane change crashes in the United States (U.S.) based on data from the 1999 National Automotive Sampling System/General Estimates System (GES) crash database of the National Highway Traffic Safety ...
Najm, W. G., Smith, J. D., Sen, B., John A. Volpe National Transportation Systems Center (U.S.)   +3 more
core