Results 161 to 170 of about 1,897,464 (299)

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

open access: yesAdvanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan   +9 more
wiley   +1 more source

[Interview with Mark Lane in Playboy Magazine #1]

open access: yes, 1966
Magazine article which appeared in Playboy Magazine. The article features an extensive interview with Mark Lane, an attorney and author, who is critical of the Warren Commission's assessment of the assassination of President ...
Dallas (Tex.). Police Department.
core  

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

Design for dressing table : sketch no. 60 [picture] /

open access: yes, 1926
Part of collection: Furniture designs for Prime Minister's Lodge and Government House, Canberra.; Inscriptions: signed "Ruth Lane-Poole, Oct 30.1926" -- in ink.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Lane Poole, Ruth, 1885-1974.
core  

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

Design for hardwood chair : sketch no. 63 [picture] /

open access: yes, 1926
Part of collection: Furniture designs for Prime Minister's Lodge and Government House, Canberra.; Inscriptions: signed "Ruth Lane-Poole, Dec.6.1926" -- in ink.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Lane Poole, Ruth, 1885-1974.
core  

Corynoxine Inhibits Tumor Growth via Targeting NQO1 and Modulating the PTPA–NQO1/PP2A Switch to Activate PP2A

open access: yesAdvanced Science, EarlyView.
Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy