A dilemma study of the traffic flow system emerged due to the lane-change by follower's tailgating effect. [PDF]
Sci RepSueyoshi F, Hossain MA, Tanimoto J.
europepmc +1 more source
Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo +13 more
wiley +1 more source
Angewandte Chemie, EarlyView.DNA structures with short single‐strand gaps in the non‐template strand of the T7 promoter prevent transcription by T7 RNA polymerase. Contrary to intuition, however, transcriptional activity can be observed again when the size of the gap increases toward the transcription start site, thereby reducing the proportion of double‐stranded DNA in the ...
Michael W. Haydell +2 more
wiley +2 more sources
Temporal dynamics in barrier-involved crashes: Determining shifts in driving behavior and injury risk across multi-year periods. [PDF]
Sci RepBarua S +5 more
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Animal Models and Experimental Medicine, EarlyView.We investigated the therapeutic potential and mechanism of chrysin in experimental diabetic retinal disease. Using a streptozotocin (STZ)‐induced diabetic mouse model and high‐glucose‐stimulated BV2 microglia, we revealed chrysin‐responsive pyroptosis‐associated signatures and identified GBP3 as a regulated node.
Qun Liu +9 more
wiley +1 more source
Mechanical Caging of Nucleic Acids Enabled by Light‐Activated Synthetic Molecular Motors
Angewandte Chemie, EarlyView.A synthetic light‐driven molecular motor imposes mechanical constraints on nucleic acids, enabling “mechanical caging” as a new mode to regulate DNA structure and function through mechanical input rather than chemical masking. ABSTRACT Control over nucleic acid activity is central to biotechnology and therapeutic development.
Yuchen Ma +10 more
wiley +2 more sources
Low-power design and implementation of an enhanced I2C bus controller using open lane: from RTL to GDSII. [PDF]
Sci RepK G, S A, V A, Velmurugan SN, M M.
europepmc +1 more source
Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome
Annals of Neurology, EarlyView.Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca +24 more
wiley +1 more source
The impact of vehicle lane-changing on the speed and delay of vehicles in the target lane based on the GMM-HMM. [PDF]
Sci RepYang Q, Li P, Lv D, Hu G, Wang X.
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Research on vehicle trajectory planning algorithm integrating spatiotemporal constraints and adaptive curvature. [PDF]
Sci RepZhao Y, Wang J, Li P, Wang H.
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