Results 161 to 170 of about 7,145,619 (284)

Corynoxine Inhibits Tumor Growth via Targeting NQO1 and Modulating the PTPA–NQO1/PP2A Switch to Activate PP2A

Advanced Science, EarlyView.
Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou, Li Lin, Mengjie Xia, Ruohan Liang, Yueyue Zhang, Linna Du, Xuan Cao   +6 more
wiley   +1 more source

Development and Field Validation of a Double-Antigen Sandwich Colloidal Gold Immunochromatographic Strip for Detection of <i>Toxoplasma gondii</i> Antibodies in Multiple Host Species. [PDF]

Transbound Emerg Dis
Mu X, Chen C, Pu X, Xu L, Lu M, Yan R, Li X, Song X.   +7 more
europepmc   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Fast-CenLaneNet: A Lightweight Instance Segmentation-Based Network for Real-Time Lane Detection. [PDF]

J Imaging
Han Q, Feng S, Gao Y, Li M, Meng T, Li K, Yang Y.   +6 more
europepmc   +1 more source

Harry Rosengrave : a retrospective exhibition : prints

, 1980
Catalogue of an exhibition held at Niagara Lane Gallery, Melbourne, 19 March - 2 April 1980Artist: Harry ...
27 Niagara Lane Gallery
core  

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

A Rapid p72-Targeting Colloidal Gold Immunochromatographic Strip for African Swine Fever Virus Detection. [PDF]

Transbound Emerg Dis
Wang W, Tesfagaber W, Zhu W, Yin L, Liu F, Yao R, Wu S, Li F, Sun E, Zhang Z, Bu Z, Meng G, Zhu Y, Zhao D.   +13 more
europepmc   +1 more source

Stabilization of Ultrafast Domain Wall Motion by Edge‐Anisotropy Engineering in Ferrimagnetic Nanowires

Advanced Electronic Materials, EarlyView.
Localized laser annealing transforms distorted, edge‐pinned domain‐wall motion in ferrimagnetic Pt/GdFe nanowires into straight, stable, and ultrafast propagation. Experiments and micromagnetic simulations reveal an optimum anisotropy‐engineering window in which moderate edge softening suppresses pinning, whereas excessive anisotropy reduction or ...
Mojtaba Mohammadi, Sina Ranjbar, Yoshinobu Nakatani, Benjamin Lilienthal‐Uhlig, Kenji Tanabe, Hiroyuki Awano   +5 more
wiley   +1 more source

Development of a Double-Antibody Sandwich ELISA for the Detection of HPV16 E6 Protein. [PDF]

Diagnostics (Basel)
Ding P, Yan M, Wang X, Wang H, Yan W, Wang Y, Zhou J, Wang A.   +7 more
europepmc   +1 more source

Enhancing Sustainability Label Effectiveness Through Logo Design Modification: An Analysis of the EU Green Leaf Logo

Agribusiness, EarlyView.
ABSTRACT Sustainability labels can help support consumers select more socially and environmentally friendly options, thereby enhancing returns for conscientious producers and promoting the transition to a more sustainable food system. However, consumer confusion regarding labels' meaning undermines their effectiveness.
Monika Hartmann, Ching‐Hua Yeh, Matthew Gorton, Barbara Tocco, Áron Török   +4 more
wiley   +1 more source