Results 111 to 120 of about 10,482,646 (332)

Optimal Dimensionality Selection Using Hull Heatmaps for Single‐Cell Analysis

open access: yesComputer Graphics Forum, EarlyView.
We propose two types of hull heatmaps to assist in selecting the optimal dimensionality in single‐cell analysis: the cell type heatmap, displaying overlaps between cell types, and the cluster heatmap, comparing cell clustering results. In quantitative evaluations, ours yielded downstream analysis results that were comparable to or better than others ...
Haejin Jeong   +3 more
wiley   +1 more source

Indeterminate cell histocytosis with naïve cells

open access: yesRare Tumors, 2013
Histiocytoses are a heterogeneous group of disorders characterized by proliferation and accumulation of cells of mononuclearmacrophage system and dendritic cells.
Sheren F Younes   +3 more
doaj   +1 more source

A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of Langerhans [PDF]

open access: yes, 2008
Background: The extracellular calcium-sensing receptor (CaR) is expressed in many tissues that are not associated with Ca2+ homeostasis, including the endocrine cells in pancreatic islets of Langerhans.
Burns, Christopher J.   +4 more
core   +1 more source

Requirements for Alternative In Vitro and In Silico Skin Models of Irritant and Allergic Contact Dermatitis

open access: yesContact Dermatitis, EarlyView.
ABSTRACT Contact dermatitis is an inflammatory disease characterised by skin redness and swelling, oozing of fluid or pus and pain, caused by direct skin contact with an irritant or allergen. Its prevalence has skyrocketed worldwide, probably because human skin is in daily contact with an increasing gamut of irritants and allergens, which should ...
Meital Portugal‐Cohen   +9 more
wiley   +1 more source

BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease. [PDF]

open access: yes, 2014
Erdheim-Chester disease (ECD) is a rare histiocytosis with a high prevalence of BRAF V600E mutation (>50% of patients). Patients with BRAF-mutant ECD can respond to BRAF inhibitors.
Cabrilo, Goran   +12 more
core   +3 more sources

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

open access: yesCell Proliferation, EarlyView.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye   +6 more
wiley   +1 more source

Adult Langerhans cell histiocytosis with pulmonary and colorectoanal involvement: a case report

open access: yesJournal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a rare systemic disease characterized by the abnormal overproduction of histiocytes that tend to infiltrate single or multiple organ systems leading to significant tissue damage. It mainly affects – by order of
Mohamad Jihad Mansour   +4 more
doaj   +1 more source

Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice [PDF]

open access: yes, 2017
Significance Our studies indicate that the resident macrophages of the pancreatic islets of Langerhans have a seminal role in the initiation and progression of autoimmune diabetes in NOD mice.
Carrero, Javier A.   +7 more
core   +2 more sources

Keratinocyte‐Derived Glucocorticoids Maintain Immune Balance During Transient Skin Barrier Perturbation

open access: yes
Allergy, EarlyView.
Truong San Phan   +6 more
wiley   +1 more source

An Unusual Case of Cutaneous Langerhans Cell Sarcoma Lacking S100 Expression: A Case Report and Review of the Literature

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Langerhans cell sarcoma (LCS) is a rare neoplastic proliferation of Langerhans cell with aggressive clinical behavior and involves multiple organ systems, including the skin. LCS is characterized by marked cytologic atypia, frequent mitoses including atypical ones, and expression of CD1a, S100, and langerin (CD207).
Randa Obid   +8 more
wiley   +1 more source

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