Results 111 to 120 of about 10,558,900 (341)

Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions

open access: yesAllergy, EarlyView.
ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller   +9 more
wiley   +1 more source

Single Cell Analysis Reveals Dynamic Changes of Distinct Cell Populations in Human Nickel Allergy

open access: yesAllergy, EarlyView.
We investigated cell types mediating the early and late inflammatory responses in human Ni2+‐allergy by scRNA‐Seq. Early responsiveness was mainly mediated by TLR4+TAGLN− endothelial cells indirectly activating TLR4−KRT16+ keratinocytes, and CCR7+DCN+ DCs. Late responsiveness was crucially driven by infiltration of KLF2+ central memory T cells and TLR4+
Marc Schmidt   +7 more
wiley   +1 more source

The Incidence of Type 1 Diabetes in Sweden During 2008–2021

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aims We analysed type 1 diabetes incidence in individuals aged 0–24 years from 2008 to 2021, with a focus on age at onset and potential changes during the COVID‐19 pandemic. Methods Type 1 diabetes incidence was assessed using insulin prescriptions from the Prescribed Drug Register.
Yazan Al Abed   +8 more
wiley   +1 more source

Influence of forest cover and sex on wing size and shape of a spider‐hunting wasp in the Brazilian Atlantic forest

open access: yesEcological Entomology, EarlyView.
Forest cover significantly influences the wing shape of female Trypoxylon lactitarse. Females exhibit longer and narrower wings, linked to greater flight efficiency and dispersal. Sexual dimorphism indicates that females respond differently to ecological pressures, underscoring the role of forest cover in species persistence.
Alexsandra de Lima Klates   +3 more
wiley   +1 more source

The Clinicopathologic Spectrum of Rosai–Dorfman–Destombes Disease in Adults: An Analysis of 16 Cases

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytic proliferation with protean clinical manifestations, resulting from the accumulation of activated histiocytes within nodal and extra‐nodal tissues. The diagnosis can be missed, particularly when biopsies are obtained from extra‐nodal sites, where histological features may be less ...
Mark Trinder   +8 more
wiley   +1 more source

Long‐term outcomes of stereotactic radiofrequency ablation in hypothalamic hamartomas: A single‐center experience

open access: yesEpilepsia, EarlyView.
Abstract Objective Hypothalamic hamartomas (HHs) lead to refractory epilepsy, and minimally invasive surgical approaches are standard of care for affected patients. Stereotactic radiofrequency thermocoagulation (SRT) is one of the treatment methods recognized to achieve seizure freedom. This study reports surgical outcome from a single center reporting
Peter Christoph Reinacher   +9 more
wiley   +1 more source

Paediatric Langerhans cell histiocytosis with diabetes insipidus: remarkable recovery journey

open access: yesJournal of the Pakistan Medical Association
A rare condition known as Langerhans cell histiocytosis (LCH) is characterised by the clonal growth of dendritic cells called Langerhans cells, which play a significant role in the immune system. A diverse range of clinical presentations are probable as
Versha Rani Rai   +4 more
doaj   +1 more source

Langerhans cell and HIV

open access: yesJapanese Journal of Clinical Immunology, 2011
Heterosexual transmission of HIV is the most common mode of infection in the global HIV epidemic. In the absence of an effective vaccine, there is an urgent need for additional strategies to prevent new HIV infections. Evidence from a variety of investigations, including epidemiologic studies on sexual transmission, in vivo studies in rhesus monkey ...
openaire   +4 more sources

Aural plaques: Considerations on autohaemotherapy treatment in four Mangalarga Marchador crossbred horses

open access: yesEquine Veterinary Education, EarlyView.
Summary The occurrence of Aural Plaques (AP) in horses, attributed to infection with Equus caballus Papillomavirus (EcPV), has become increasingly prevalent in equine breeding populations. Major challenges in managing this condition include genetic susceptibility to the virus, significant variability in individual immune responses among horses and the ...
E. Bastianetto   +6 more
wiley   +1 more source

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