Results 141 to 150 of about 10,554,839 (372)

Langerhans cell histiocytosis: Two clinical presentations in the same patient [PDF]

, 2012
Langerhans cell histiocytosis (LCH) is a heterogeneous group of diseases characterized by a pathological proliferation of cells phenotypically similar to Langerhans cells.
Lobo, I., Machado, S., Oliveira, A., Pinto-Almeida, T., Selores, M.   +4 more
core   +1 more source

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. [PDF]

, 1995
Insulin-dependent diabetes mellitus (IDDM) is thought to be an immunologically mediated disease resulting in the complete destruction of the insulin-producing islets of Langerhans.
Bluestone, JA, Gray, G, Herold, KC, Ho, SC, Lenschow, DJ, Nabavi, N, Rhee, L, Sattar, H   +7 more
core  

The Clinicopathologic Spectrum of Rosai–Dorfman–Destombes Disease in Adults: An Analysis of 16 Cases

European Journal of Haematology, EarlyView.
ABSTRACT Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytic proliferation with protean clinical manifestations, resulting from the accumulation of activated histiocytes within nodal and extra‐nodal tissues. The diagnosis can be missed, particularly when biopsies are obtained from extra‐nodal sites, where histological features may be less ...
Mark Trinder, Collin Pryma, Emily Leung, Graham W. Slack, Pedro Farinha, Sean Young, Neval Ozkaya, Mollie Carruthers, Luke Y. C. Chen   +8 more
wiley   +1 more source

An Unusual Case of Cutaneous Langerhans Cell Sarcoma Lacking S100 Expression: A Case Report and Review of the Literature. [PDF]

J Cutan Pathol
ABSTRACT Langerhans cell sarcoma (LCS) is a rare neoplastic proliferation of Langerhans cell with aggressive clinical behavior and involves multiple organ systems, including the skin. LCS is characterized by marked cytologic atypia, frequent mitoses including atypical ones, and expression of CD1a, S100, and langerin (CD207).
Obid R, Green AR, Jasmine SW, Kowal RP, Abro B, Warmke LM, Czader MB, Alomari AK, Dehner CA.   +8 more
europepmc   +2 more sources

UNIVERSITY STUDENTS’ PERCEPTIONS TOWARD “PAIRED AND PROBLEMS LEARNING METHOD” IN WRITING CLASS. [PDF]

Language is a communicative system as a medium for expressing thoughts and emotions, without language humans cannot connect with each other. Student perceptions refer to the way students understand and interpret information, experiences or situations ...
Rahayu, Agung Lita
core  

Aural plaques: Considerations on autohaemotherapy treatment in four Mangalarga Marchador crossbred horses

Equine Veterinary Education, EarlyView.
Summary The occurrence of Aural Plaques (AP) in horses, attributed to infection with Equus caballus Papillomavirus (EcPV), has become increasingly prevalent in equine breeding populations. Major challenges in managing this condition include genetic susceptibility to the virus, significant variability in individual immune responses among horses and the ...
E. Bastianetto, M. I. de Azevedo, I. S. Ferrão, P. Fantini, E. M. M. Lima, M. B. Castro, C. B. de Melo   +6 more
wiley   +1 more source

Skin‐Derived PGD2 Promotes Antigen‐Specific IgE Production via CRTH2 Signaling

Allergy, EarlyView.
Misato Kida, Tatsuro Nakamura, Shingo Maeda, Nanae Nagata, Hirofumi Enomoto, Takahisa Murata   +5 more
wiley   +1 more source

MSC‐Derived Secretome and Exosomes in Dermatology: Mechanisms, Therapeutic Opportunities, and Scientific Challenges—A Narrative Review

International Journal of Dermatology, EarlyView.
ABSTRACT Mesenchymal stromal cells (MSCs) exert their effects primarily through paracrine signaling via soluble factors and extracellular vesicles (EVs), especially exosomes. These acellular components offer regenerative and immunomodulatory benefits with fewer safety and logistical constraints than cell‐based therapies.
Marcela da Costa Pereira Cestari, Reinaldo Falavigna Tovo, Daniela Franco Bueno   +2 more
wiley   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, EarlyView.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev, Nagore Ambrosio, Cheryl Somani, Elena Figuero, Lior Shapira, Janet Davies   +5 more
wiley   +1 more source