Results 141 to 150 of about 4,942,068 (276)
Adult langerhans cell histiocytosis
Langerhans cell histiocytosis is a group of idiopathic disorders characterized by the abnormal proliferation of specialized bone marrow-derived Langerhans cells. There are one to two cases per million population.
Bahceci, Mithat +4 more
core +1 more source
d‐Sorbose promotes Foxp3+ Treg differentiation ex vivo and exerts potent anti‐inflammatory effects in vivo, ameliorating allergic airway inflammation and preventing autoimmune diabetes without compromising T cell viability or inducing toxicity.
Fumiaki Sato +12 more
wiley +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
ABSTRACT Introduction Children treated with ifosfamide seem to have an increased risk for developing chronic kidney disease (CKD) already within the first years following chemotherapy. However, studies investigating CKD prevalence in this specific phase are scarce.
Lotte Pitlo +9 more
wiley +1 more source
IL‐22Rα1 restrains pancreatic injury independently of its C‐terminal STAT3‐amplifying domain
IL‐22R, and to a lesser extent IL‐22, are key drivers of protection in acute pancreatitis. Although the C‐terminal domain of IL‐22R enhances STAT3 activation in the pancreas, it is not required for disease protection. Classical IL‐22R signaling alone is sufficient to control inflammation and promote pancreatic recovery.
Léna Puigdevall +4 more
wiley +1 more source
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani +4 more
wiley +1 more source
[Stammbuch Heinrich Langerhans] [PDF]
[STAMMBUCH HEINRICH LANGERHANS] [Stammbuch Heinrich Langerhans] ( - ) Cover ( - ) Notiz und Liste von zehn Einträgern (0v 1r) Thomasius, Christian; Blatt 3 (2v 3r) Ludewig, Johann Peter von; Blatt 4 (3v 4r) Klausing ...
Langerhans, Heinrich
core
Langerhans cell histiocytosis (LCH) is a rare disease involving multiple systems, and it is caused by excessive proliferation of Langerhans cells. The hypothalamic-pituitary region (HPR) is involved in 5%-50% of all LCH patients, particularly those with ...
Murat Şahin +3 more
core +1 more source
HAR may improve T2DM by enhancing antioxidant defences through Nrf2 activation while suppressing inflammation and RAS activity, supporting its capability to treat diabetes. ABSTRACT Introduction Type 2 diabetes mellitus (T2DM) is strongly associated with oxidative stress and inflammation.
Farima Malekinia +5 more
wiley +1 more source

