Results 301 to 310 of about 10,482,646 (332)
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Immunology & Cell Biology, 2010
Langerhans cells (LCs) are the resident dendritic cells (DCs) of epidermis in human mucosal stratified squamous epithelium and the skin. A phenotypically similar DC has recently been discovered as a minor population in the murine dermis. In epidermis, LCs function as sentinel antigen‐presenting cells that can capture invading viruses such as herpes ...
Najla Nasr+8 more
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Langerhans cells (LCs) are the resident dendritic cells (DCs) of epidermis in human mucosal stratified squamous epithelium and the skin. A phenotypically similar DC has recently been discovered as a minor population in the murine dermis. In epidermis, LCs function as sentinel antigen‐presenting cells that can capture invading viruses such as herpes ...
Najla Nasr+8 more
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Neuropeptides and Langerhans cells
Experimental Dermatology, 1998Abstract: The immune system and nervous system are intimately related. In addition to neuroendocrine mechanisms, neuropeptides have a variety of effects on immune cells and are responsible at least in part for neurogenic inflammation. The presence of neuropeptides in the skin has been well documented. The influence of neuropeptides on Langerhans cells
Richard D. Granstein, R. W. Lambert
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Archives of Disease in Childhood, 2009
Langerhans cell histiocytosis is a rare disease. Depending on which organs are involved, the disease may prove rapidly fatal, develop a chronic reactivating but therapy-responsive pattern or resolve spontaneously. Understanding of the pathology of the disease is progressing rapidly, and while clinical trials of standard chemotherapy agents continue, it
Kevin Windebank, Vasanta Nanduri
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Langerhans cell histiocytosis is a rare disease. Depending on which organs are involved, the disease may prove rapidly fatal, develop a chronic reactivating but therapy-responsive pattern or resolve spontaneously. Understanding of the pathology of the disease is progressing rapidly, and while clinical trials of standard chemotherapy agents continue, it
Kevin Windebank, Vasanta Nanduri
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More than just Langerhans cell histiocytosis: a radiologic review of histiocytic disorders.
Radiographics, 2014Although Langerhans cell histiocytosis (LCH) is a familiar entity to most radiologists and to pediatric radiologists in particular, it is but one of a group of disorders caused by the overproduction of histiocytes, a subtype of white blood cells.
J. Zaveri+3 more
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Journal of Cutaneous Medicine and Surgery, 2012
Background: The cutaneous presentation of Langerhans cell histiocytosis (LCH) is very rare and can be highly variable among individuals, which can often lead to a delay in diagnosis. Objective: To discuss a case report and literature review of important clinical indicators, histology, diagnosis, evaluation, and treatment guidelines.
Clayton Schiltz+2 more
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Background: The cutaneous presentation of Langerhans cell histiocytosis (LCH) is very rare and can be highly variable among individuals, which can often lead to a delay in diagnosis. Objective: To discuss a case report and literature review of important clinical indicators, histology, diagnosis, evaluation, and treatment guidelines.
Clayton Schiltz+2 more
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Langerhans’ Cell Histiocytosis
Orthopedic Clinics of North America, 1996Langerhans' Cell Histiocytosis, formerly known as Histiocytosis X, and its related syndromes (i.e., eosinophilic granuloma, Hand-Schuller-Christian disease, and Letterer-Siwe disease) are briefly reviewed. The biology, clinical manifestations, and treatment options of the localized, single form and the disseminated, multisystem form are also discussed.
Maria C. Velez-Yanguas, Raj Warrier
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Journal of the American Academy of Dermatology, 2001
From the Department of Radiology, Division of Neuroradiology,a and the Department of Dermatology,b Indiana University Medical Center; and the Department of Oral Surgery Medicine and Pathology, Indiana University School of Dentistry.c Reprint requests: Ginat W. Mirowski, DMD, MD, Department of Dermatology, 550 N University Blvd, Suite 3240, Indianapolis,
Ginat W. Mirowski+2 more
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From the Department of Radiology, Division of Neuroradiology,a and the Department of Dermatology,b Indiana University Medical Center; and the Department of Oral Surgery Medicine and Pathology, Indiana University School of Dentistry.c Reprint requests: Ginat W. Mirowski, DMD, MD, Department of Dermatology, 550 N University Blvd, Suite 3240, Indianapolis,
Ginat W. Mirowski+2 more
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Pathogenesis of Langerhans cell histiocytosis.
Annual Review of Pathology, 2013Langerhans cell histiocytosis (LCH) combines in one nosological category a group of diseases that have widely disparate clinical manifestations but are all characterized by accumulation of proliferating cells with surface markers and ultrastructural ...
G. Badalian‐Very+3 more
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Current Opinion in Hematology, 1998
The term histiocytosis identifies a group of disorders characterized by localized or generalized reactive or neoplastic proliferation of cells similar, if not identical, to cells of the mononuclear phagocyte and dendritic cell systems. In Langerhans cell histiocytosis (LCH), the proliferating cell is the Langerhans cell, and the morphologic and ...
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The term histiocytosis identifies a group of disorders characterized by localized or generalized reactive or neoplastic proliferation of cells similar, if not identical, to cells of the mononuclear phagocyte and dendritic cell systems. In Langerhans cell histiocytosis (LCH), the proliferating cell is the Langerhans cell, and the morphologic and ...
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The immunobiology of Langerhans cells
Immunology Today, 1981Interest in the biology of Langerhans cells has recently been stimulated by observations, reviewed here by Peter Friedmann, that they are active members o f the immune system.
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