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Addendum: RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions. [PDF]
Hogstad B +23 more
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Age-Stratified Imaging Selection in Langerhans Cell Histiocytosis: Towards a Clinical Decision Framework. [PDF]
Gettleman B +10 more
europepmc +1 more source
Langerhans' cell histiocytosis
A 38-year-old woman complained of persistent chest pain. A plain radiograph showed an irregularity on the sternum, and bone-scan showed uptake only in that area. Thoracic-abdominal CT showed an osteolytic lesion of the sternum (figure) without any other signs of neoplasia.
N. Fazio +4 more
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Adult Langerhans cell histiocytosis
European Journal of Haematology, 2006Abstract:  Langerhans cell histiocytosis (LCH) is a proliferative histiocytic disorder of unknown cause originating from dendritic cells. The clinical presentation of LCH is highly variable. Although the features of this disease have been well described in children, they remain poorly defined in adults. Here, we review the current knowledge about adult
Marcus, Stockschlaeder +1 more
exaly +3 more sources
Biology of Langerhans Cells and Langerhans Cell Histiocytosis
International Review of Cytology, 2006Langerhans cells (LC) are epidermal dendritic cells (DC). They play an important role in the initiation of immune responses through antigen uptake, processing, and presentation to T cells. Langerhans cell histiocytosis (LCH) is a rare disease in which accumulation of cells with LC characteristics (LCH cells) occur. LCH lesions are further characterized
R J Arceci, R M Egeler
exaly +3 more sources
Journal of the American Academy of Dermatology, 2001
From the Department of Radiology, Division of Neuroradiology,a and the Department of Dermatology,b Indiana University Medical Center; and the Department of Oral Surgery Medicine and Pathology, Indiana University School of Dentistry.c Reprint requests: Ginat W. Mirowski, DMD, MD, Department of Dermatology, 550 N University Blvd, Suite 3240, Indianapolis,
K S, Caldemeyer +2 more
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From the Department of Radiology, Division of Neuroradiology,a and the Department of Dermatology,b Indiana University Medical Center; and the Department of Oral Surgery Medicine and Pathology, Indiana University School of Dentistry.c Reprint requests: Ginat W. Mirowski, DMD, MD, Department of Dermatology, 550 N University Blvd, Suite 3240, Indianapolis,
K S, Caldemeyer +2 more
+7 more sources
Dermatology, 2009
Langerhans cell histiocytosis is a rare disease. Depending on which organs are involved, the disease may prove rapidly fatal, develop a chronic reactivating but therapy-responsive pattern or resolve spontaneously. Understanding of the pathology of the disease is progressing rapidly, and while clinical trials of standard chemotherapy agents continue, it
K, Windebank, V, Nanduri
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Langerhans cell histiocytosis is a rare disease. Depending on which organs are involved, the disease may prove rapidly fatal, develop a chronic reactivating but therapy-responsive pattern or resolve spontaneously. Understanding of the pathology of the disease is progressing rapidly, and while clinical trials of standard chemotherapy agents continue, it
K, Windebank, V, Nanduri
openaire +4 more sources
Langerhans’ Cell Histiocytosis
Orthopedic Clinics of North America, 1996Langerhans' Cell Histiocytosis, formerly known as Histiocytosis X, and its related syndromes (i.e., eosinophilic granuloma, Hand-Schuller-Christian disease, and Letterer-Siwe disease) are briefly reviewed. The biology, clinical manifestations, and treatment options of the localized, single form and the disseminated, multisystem form are also discussed.
M C, Velez-Yanguas, R P, Warrier
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