Results 181 to 190 of about 4,903,700 (215)
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Langerhans cell histiocytosis

The Journal of Pediatrics, 1995
The first major stride toward understanding LCH was taken when ultrastructural studies identified the proliferating cells as part of the Langerhans (dendritic) cell system. Another step forward was the definition of the morphologic, immunohistochemical, and clinical criteria needed for the diagnosis of LCH.
R M, Egeler, G J, D'Angio
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Langerhans Cell Histiocytosis

Journal of Cutaneous Medicine and Surgery, 2012
Background: The cutaneous presentation of Langerhans cell histiocytosis (LCH) is very rare and can be highly variable among individuals, which can often lead to a delay in diagnosis. Objective: To discuss a case report and literature ...
Ligaya, Park   +2 more
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Langerhans Cell Histiocytosis

New England Journal of Medicine, 1987
Nearly a century has passed since Alfred Hand reported a case of "polyuria and tuberculosis,"1 later considered to be the first case of the Hand-Schul1er–Christian syndrome.
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THE EPIDEMIOLOGY OF LANGERHANS CELL HISTIOCYTOSIS

Hematology/Oncology Clinics of North America, 1998
Little progress has been made in finding the causes of LCH. Epidemiologic studies are difficult because of the rarity of this disease. Although several associations have been demonstrated in case-control studies, particularly that with thyroid disease, no causal relationships have been documented. Additional case-control studies may uncover the to-date
Nicholson, HS, Egeler, RM, Nesbit, ME
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Differentiation of Langerhans cells in Langerhans cell histiocytosis

Blood, 2001
Langerhans cell histiocytosis (LCH) consists of lesions composed of cells with a dendritic Langerhans cell (LC) phenotype. The clinical course of LCH ranges from spontaneous resolution to a chronic and sometimes lethal disease. We studied 25 patients with various clinical forms of the disease.
F, Geissmann   +8 more
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Langerhans' cells histiocytosis.

International journal of pediatric otorhinolaryngology, 1999
Langerhans cell histiocytosis (LCH) is a rare disorder of unknown cause, characterized by the proliferation of histiocytic cells in various tissues and organs. The role of the otolaryngologist is important in the early and accurate evaluation, staging and diagnosis of LCH, because it may mimic more common diseases such as otitis externa and acute ...
SELLARI FRANCESCHINI, STEFANO   +5 more
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Langerhans' cell histiocytosis cells are activated langerhans' cells

The Journal of Pathology, 1994
AbstractLangerhans' cell histiocytosis (LCH) is characterized by the presence of large mononucleated cells, associated with inflammatory cells. The Langerhans' cell (LC) lineage of the mononucleated cells is suggested by the presence of Birbeck granules and the expression of CD1a.
J F, Emile   +4 more
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LANGERHANS CELL HISTIOCYTOSIS OF THE SKIN

Hematology/Oncology Clinics of North America, 1998
Cutaneous involvement in Langerhans cell histiocytosis (LCH) occurs in 50% of cases and may be the presenting feature. It is, therefore, important to recognize the wide spectrum of clinical disease that this disorder may adopt in the skin. Cutaneous involvement is not necessarily a benign feature and many patients progress to multi-system disease ...
S, Munn, A C, Chu
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LANGERHANS CELL HISTIOCYTOSIS IN ADULTS

Hematology/Oncology Clinics of North America, 1998
Langerhans cell histiocytosis in the adult is rare, but it is important to recognize its occurrence, as it must be differentiated from lymphoma, myeloma, and a variety of skin conditions and endocrinopathies. It has been reported in patients up to the ninth decade of life, and occurs equally in men and women.
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