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Langerhans Cell Histiocytosis

Journal of Cutaneous Medicine and Surgery, 2012
Background: The cutaneous presentation of Langerhans cell histiocytosis (LCH) is very rare and can be highly variable among individuals, which can often lead to a delay in diagnosis. Objective: To discuss a case report and literature ...
Ligaya, Park   +2 more
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THE EPIDEMIOLOGY OF LANGERHANS CELL HISTIOCYTOSIS

Hematology/Oncology Clinics of North America, 1998
Little progress has been made in finding the causes of LCH. Epidemiologic studies are difficult because of the rarity of this disease. Although several associations have been demonstrated in case-control studies, particularly that with thyroid disease, no causal relationships have been documented. Additional case-control studies may uncover the to-date
Nicholson, HS, Egeler, RM, Nesbit, ME
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Langerhans' cells histiocytosis.

International journal of pediatric otorhinolaryngology, 1999
Langerhans cell histiocytosis (LCH) is a rare disorder of unknown cause, characterized by the proliferation of histiocytic cells in various tissues and organs. The role of the otolaryngologist is important in the early and accurate evaluation, staging and diagnosis of LCH, because it may mimic more common diseases such as otitis externa and acute ...
SELLARI FRANCESCHINI, STEFANO   +5 more
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Differentiation of Langerhans cells in Langerhans cell histiocytosis

Blood, 2001
Langerhans cell histiocytosis (LCH) consists of lesions composed of cells with a dendritic Langerhans cell (LC) phenotype. The clinical course of LCH ranges from spontaneous resolution to a chronic and sometimes lethal disease. We studied 25 patients with various clinical forms of the disease.
F, Geissmann   +8 more
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Langerhans' cell histiocytosis cells are activated langerhans' cells

The Journal of Pathology, 1994
AbstractLangerhans' cell histiocytosis (LCH) is characterized by the presence of large mononucleated cells, associated with inflammatory cells. The Langerhans' cell (LC) lineage of the mononucleated cells is suggested by the presence of Birbeck granules and the expression of CD1a.
J F, Emile   +4 more
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Langerhans cell histiocytosis and dermatophytosis

Journal of the American Academy of Dermatology, 1993
Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, scaling and erythema may also be ...
A S, Pakula, A S, Paller
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LANGERHANS CELL HISTIOCYTOSIS OF THE SKIN

Hematology/Oncology Clinics of North America, 1998
Cutaneous involvement in Langerhans cell histiocytosis (LCH) occurs in 50% of cases and may be the presenting feature. It is, therefore, important to recognize the wide spectrum of clinical disease that this disorder may adopt in the skin. Cutaneous involvement is not necessarily a benign feature and many patients progress to multi-system disease ...
S, Munn, A C, Chu
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Biology of Langerhans Cells and Langerhans Cell Histiocytosis

2006
Langerhans cells (LC) are epidermal dendritic cells (DC). They play an important role in the initiation of immune responses through antigen uptake, processing, and presentation to T cells. Langerhans cell histiocytosis (LCH) is a rare disease in which accumulation of cells with LC characteristics (LCH cells) occur. LCH lesions are further characterized
G I, Bechan, R M, Egeler, R J, Arceci
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Langerhans cell histiocytosis with disequilibrium

Auris Nasus Larynx, 2012
Langerhans cell histiocytosis (LCH) is a very rare disease in which granulation tissue forms in various organs and the central nervous system (CNS) due to monoclonal proliferation of Langerhans cells. Some patients develop ataxia, tremor, or neurodegenerative abnormalities (such as personality changes and mental deterioration) several years after the ...
Tomoe, Nakamura   +6 more
openaire   +2 more sources

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