Results 91 to 100 of about 39,048 (228)
Modeling of reaction-diffusion transport into a core-shell geometry [PDF]
Fickian diffusion into a core-shell geometry is modeled. The interior core mimics pancreatic Langerhan islets and the exterior shell acts as inert protection.
Beckman, S. +5 more
core +3 more sources
Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes [PDF]
Objectives: One of the theories connecting enterovirus (EV) infection of human islets with type 1 diabetes (T1D) is the development of a fertile field in the islets.
Alhazmi, A +69 more
core +1 more source
Transplantation or islets of Langerhans: new developments
The clinical results recently reported by the Edmonton group in recipients of allogeneic islet grafts, all of whom achieved at least temporary insulin independence, has rekindled interest in transplantation of islets of Langerhans as a means to cure diabetes.
Berney, Thierry +8 more
openaire +3 more sources
A Supportive Role of Mesenchymal Stem Cells on Insulin-Producing Langerhans Islets with a Specific Emphasis on The Secretome. [PDF]
Sionov RV, Ahdut-HaCohen R.
europepmc +1 more source
Fusion of secretory vesicles isolated from rat liver [PDF]
Secretory vesicles isolated from rat liver were found to fuse after exposure to Ca2+. Vescle fusion is characterized by the occurrence of twinned vesicles with a continuous cleavage plane between two vesicles in freeze-fracture electron microscopy.
A. Amsterdam +75 more
core +1 more source
Isolation of Adult Porcine Islets of Langerhans
While human islet allotransplantation is limited due to the shortage of donors, pig islet xenotransplantation appears to be a possible alternative. Enzymatic digestion is the method most commonly used for adult pig islet isolation, but since the description of the semiautomated isolation technique in the late 1980s, yields of pig islet isolations have ...
Toso, Christian +5 more
openaire +5 more sources
Background: Tissue transplantation plays a pivotal role in the treatment of diseases. Pancreatic beta cell transplantation is the best way to obtain normal blood glucose in patients with diabetes type 1.
Rostam Ghorbani +3 more
doaj +1 more source
Single-cell imaging of α and β cell metabolic response to glucose in living human Langerhans islets. [PDF]
Azzarello F +7 more
europepmc +1 more source
The Cells of the Islets of Langerhans [PDF]
Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A number of new studies have pointed to the potential for conversion of non-β islet cells in to insulin-producing β-cells to replenish β-cell mass as a means to treat diabetes.
openaire +4 more sources

