Results 111 to 120 of about 39,048 (228)

The Diabetic Dog as a Translational Model for Human Islet Transplantation. [PDF]

, 2017
The dog model has served as the primary method for early development of many diabetes therapies, including pancreatic islet transplantation techniques and immunosuppressive protocols.
Adin, Christopher A, Gilor, Chen
core  

In Utero Exposure to Gestational Diabetes Alters DNA Methylation and Gene Expression of CDKN2A/B in Langerhans Islets of Rat Offspring. [PDF]

Cell J, 2020
Nazari Z, Shahryari A, Ghafari S, Nabiuni M, Golalipour MJ.   +4 more
europepmc   +1 more source

Effectiveness of Spatholobus littoralis Hassk Stem Extract in Repairing Islets of Langerhans Damage in a Diabetic Rat Model

Biomolecular and Health Science Journal
Introduction: Hyperglycemia, driven by insulin resistance and beta-cell dysfunction, is a hallmark of diabetes mellitus, a common chronic disease. The pancreatic islets of Langerhans are frequently harmed as a result.
Lia Amalia, Siti Khaerunnisa, Ira Humairah, Joni Susanto, Ervi Audina Munthe, Sahar Van Dyk   +5 more
doaj   +1 more source

Integrating the inputs that shape pancreatic islet hormone release. [PDF]

, 2019
The pancreatic islet is a complex mini organ composed of a variety of endocrine cells and their support cells, which together tightly control blood glucose homeostasis.
Huising, Mark O, Noguchi, Glyn M
core  

Membrane permeabilization by Islet Amyloid Polypeptide

, 2009
Membrane permeabilization by Islet Amyloid Polypeptide (IAPP) is suggested to be the main mechanism for IAPP-induced cytotoxicity and death of insulin-producing -cells in type 2 diabetes mellitus (T2DM).
Engel, Maarten F.M.
core   +1 more source

The effect of acute psychological stress on insulin release ability from rat isolated pancreatic islets

Iranian South Medical Journal, 2014
Background: Nowadays according to our life style high percent of people are exposed to different acute stressors which may result in various metabolic disorders.
Fatemeh Rostamkhani, Homeyra Zardooz, Saleh Zahediasl   +2 more
doaj  

The extra-islet pancreas supports autoimmunity in human type 1 diabetes

eLife
In autoimmune type 1 diabetes (T1D), immune cells infiltrate and destroy the islets of Langerhans — islands of endocrine tissue dispersed throughout the pancreas. However, the contribution of cellular programs outside islets to insulitis is unclear. Here,
Graham L Barlow, Christian M Schürch, Salil S Bhate, Darci J Phillips, Arabella Young, Shen Dong, Hunter A Martinez, Gernot Kaber, Nadine Nagy, Sasvath Ramachandran, Janet Meng, Eva Korpos, Jeffrey A Bluestone, Garry P Nolan, Paul L Bollyky   +14 more
doaj   +1 more source

Islet of Langerhans [PDF]

, 2020
openaire   +1 more source

Mechanistic assessment of cadmium toxicity in association with the functions of estrogen receptors in the Langerhans islets. [PDF]

Iran J Basic Med Sci, 2019
Mohammadi P, Rahimifard M, Baeeri M, Abdollahi M, Mostafalou S.   +4 more
europepmc   +1 more source

Emerging approaches for the development of artificial islets

Smart Medicine
The islet of Langerhans, functioning as a “mini organ”, plays a vital role in regulating endocrine activities due to its intricate structure. Dysfunction in these islets is closely associated with the development of diabetes mellitus (DM).
Jingbo Li, Lingyu Sun, Feika Bian, Stephen J. Pandol, Ling Li   +4 more
doaj   +1 more source