Insights into etiology and management of a case of Langerhans cell histiocytosis manifesting as perianal lesions: a case report. [PDF]
Xiao-Yue P, Zixin T, Wen-Jun Z.
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Absence of Langerhans cells resulted in over-influx of neutrophils and increased bacterial burden in skin wounds. [PDF]
Wang ZC, Hu YY, Shen XZ, Tan WQ.
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The Role of Glycans in Human Immunity-A Sweet Code. [PDF]
Tvaroška I.
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Natriuretic peptides modulate monocyte-derived Langerhans cell differentiation and promote a migratory phenotype. [PDF]
Horváth D +12 more
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Airway basal stem cells are necessary for the maintenance of functional intraepithelial airway macrophages. [PDF]
Kooistra T +35 more
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GAG Multivalent Systems to Interact with Langerin
Current Medicinal Chemistry, 2022: Langerin is a C-type Lectin expressed at the surface of Langerhans cells, which play a pivotal role protecting organisms against pathogen infections. To address this aim, Langerin presents at least two recognition sites, one Ca2+-dependent and another one independent, which are capable to recognize a variety of carbohydrate ligands.
Javier Rojo +2 more
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Langerin functions as an antiviral receptor on Langerhans cells
Immunology & Cell Biology, 2010Langerhans cells (LC) are the first dendritic cells (DC) to encounter pathogens entering the body via mucosa or skin. Equipped with pattern recognition receptors (PRR), LC are able to detect and respond to these pathogens. An important PRR, in human exclusively expressed by LC, is the C‐type lectin Langerin.
Michiel van der Vlist +1 more
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Asymmetrically Branched Precision Glycooligomers Targeting Langerin
Biomacromolecules, 2019Asymmetrically branched precision glycooligomers are synthesized by solid-phase polymer synthesis for studying multivalent carbohydrate-protein interactions. Through the stepwise assembly of Fmoc-protected oligo(amidoamine) building blocks and Fmoc/Dde-protected lysine, straightforward variation of structural parameters such as the number and length of
Eike-Christian Wamhoff +6 more
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Structural Studies of Langerin and Birbeck Granule: A Macromolecular Organization Model
Biochemistry, 2009Dendritic cells, a sentinel immunity cell lineage, include different cell subsets that express various C-type lectins. For example, epidermal Langerhans cells express langerin, and some dermal dendritic cells express DC-SIGN. Langerin is a crucial component of Birbeck granules, the Langerhans cell hallmark organelle, and may have a preventive role ...
Thepaut, M. +11 more
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