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Histiocytic Sarcoma Arising in a Background of Nodular Lymphocyte Predominant Hodgkin Lymphoma. [PDF]
Case Rep HematolWymer GEY, Ferra S, Naeem M.
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Application of langerine in diagnostics of histocytoses in children
Polish Journal of Pathology, 2005 openaire
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GAG Multivalent Systems to Interact with Langerin
Current Medicinal Chemistry, 2022: Langerin is a C-type Lectin expressed at the surface of Langerhans cells, which play a pivotal role protecting organisms against pathogen infections. To address this aim, Langerin presents at least two recognition sites, one Ca2+-dependent and another one independent, which are capable to recognize a variety of carbohydrate ligands.
Javier Rojo +2 more
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Asymmetrically Branched Precision Glycooligomers Targeting Langerin
Biomacromolecules, 2019Asymmetrically branched precision glycooligomers are synthesized by solid-phase polymer synthesis for studying multivalent carbohydrate-protein interactions. Through the stepwise assembly of Fmoc-protected oligo(amidoamine) building blocks and Fmoc/Dde-protected lysine, straightforward variation of structural parameters such as the number and length of
Kira Neuhaus +5 more
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Langerin functions as an antiviral receptor on Langerhans cells
Immunology & Cell Biology, 2010Langerhans cells (LC) are the first dendritic cells (DC) to encounter pathogens entering the body via mucosa or skin. Equipped with pattern recognition receptors (PRR), LC are able to detect and respond to these pathogens. An important PRR, in human exclusively expressed by LC, is the C‐type lectin Langerin.
Michiel, van der Vlist +1 more
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Langerin‐expressing dendritic cells in gut‐associated lymphoid tissues
Immunological Reviews, 2010Summary: Dendritic cells (DCs) are key regulators of the immune system. They act as professional antigen‐presenting cells and are capable of activating naive T cells and stimulating the growth and differentiation of B cells. According to their molecular expression, DCs can be divided into several subsets with different functions.
Sun-Young, Chang, Mi-Na, Kweon
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19F NMR-Guided Design of Glycomimetic Langerin Ligands
ACS Chemical Biology, 2016C-type lectin receptors (CLRs) play a pivotal role in pathogen defense and immune homeostasis. Langerin, a CLR predominantly expressed on Langerhans cells, represents a potential target receptor for the development of anti-infectives or immunomodulatory therapies.
Wamhoff, E. +6 more
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High affinity sugar ligands of C-type lectin receptor langerin
Biochimica et Biophysica Acta (BBA) - General Subjects, 2018Langerin, a C-type lectin receptor (CLR) expressed in a subset of dendritic cells (DCs), binds to glycan ligands for pathogen capture and clearance. Previous studies revealed that langerin has an unusual binding affinity toward 6-sulfated galactose (Gal), a structure primarily found in keratan sulfate (KS).
Ota, F. +17 more
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Intestinal Regulation of C. albicans by PP Langerin+ DCs
The Journal of Immunology, 2017Abstract As the largest mucosal compartment, the human gastrointestinal tract (GI) is highly colonized with a complex microbial ecosystem that includes fungal organisms. Although fewer in numbers and less extensively studied in the context of the intestinal mucosa, it is unclear whether commensal members such as Candida species play a ...
Magdia De Jesus +2 more
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