Results 211 to 220 of about 8,360 (233)

Natriuretic peptides modulate monocyte-derived Langerhans cell differentiation and promote a migratory phenotype. [PDF]

open access: yesFront Immunol
Horváth D   +12 more
europepmc   +1 more source

Airway basal stem cells are necessary for the maintenance of functional intraepithelial airway macrophages. [PDF]

open access: yesCell Rep
Kooistra T   +35 more
europepmc   +1 more source
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GAG Multivalent Systems to Interact with Langerin

Current Medicinal Chemistry, 2022
: Langerin is a C-type Lectin expressed at the surface of Langerhans cells, which play a pivotal role protecting organisms against pathogen infections. To address this aim, Langerin presents at least two recognition sites, one Ca2+-dependent and another one independent, which are capable to recognize a variety of carbohydrate ligands.
Javier Rojo   +2 more
openaire   +3 more sources

Langerin functions as an antiviral receptor on Langerhans cells

Immunology & Cell Biology, 2010
Langerhans cells (LC) are the first dendritic cells (DC) to encounter pathogens entering the body via mucosa or skin. Equipped with pattern recognition receptors (PRR), LC are able to detect and respond to these pathogens. An important PRR, in human exclusively expressed by LC, is the C‐type lectin Langerin.
Michiel van der Vlist   +1 more
openaire   +3 more sources

Asymmetrically Branched Precision Glycooligomers Targeting Langerin

Biomacromolecules, 2019
Asymmetrically branched precision glycooligomers are synthesized by solid-phase polymer synthesis for studying multivalent carbohydrate-protein interactions. Through the stepwise assembly of Fmoc-protected oligo(amidoamine) building blocks and Fmoc/Dde-protected lysine, straightforward variation of structural parameters such as the number and length of
Eike-Christian Wamhoff   +6 more
openaire   +3 more sources

Structural Studies of Langerin and Birbeck Granule: A Macromolecular Organization Model

Biochemistry, 2009
Dendritic cells, a sentinel immunity cell lineage, include different cell subsets that express various C-type lectins. For example, epidermal Langerhans cells express langerin, and some dermal dendritic cells express DC-SIGN. Langerin is a crucial component of Birbeck granules, the Langerhans cell hallmark organelle, and may have a preventive role ...
Thepaut, M.   +11 more
openaire   +3 more sources

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