Results 91 to 100 of about 19,326,132 (286)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Malaysia Madani in the light of Islamic Values: Understanding and Acceptance of Malaysians

open access: yesIslamiyyat
Malaysia Madani is a policy framework and government slogan established under the leadership of Anwar Ibrahim, Malaysia’s tenth prime minister. The concept mainly encompasses sound governance, sustainable development, and racial harmony in the country.
Nor Hazwani Munirah Lateh   +4 more
doaj   +1 more source

On The Validity Of Exploiting The Basic Concepts Of Arabic Linguistics For The Analysis Of English

open access: yesAl-Lisaniyyat, 2005
This paper aims at discussing the possibility of exploiting the basic concepts of Arabic linguistics for the analysis of a language other than Arabic, namely English.
Fatiha Khelout   +2 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Power and marginalization in discourse on AI in education (AIEd): social actors’ representation in China Daily (2018–2023)

open access: yesHumanities & Social Sciences Communications
Artificial Intelligence in Education (AIEd) has the potential to transform educational practice, and its media representation both reflects and reshapes public perceptions of this new technology.
Xi Huang, Savitri Gadavanij
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Cognate Effects on Bilingual Lexical–Semantic Processing in Children: Insights from ERPs

open access: yesBehavioral Sciences
This study investigates whether and, if so, how cognates facilitate lexical–semantic processing during early bilingual development. Additionally, we examine the interaction between the cognate facilitation effect (CFE) and bilingual experience factors ...
Chih Yeh   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Individual Differences in Global Cognition Modulate the Effect of Motor-Relatedness on Object Naming in Healthy Older Adults

open access: yesBehavioral Sciences
Lexical retrieval difficulty is a common daily complaint among older adults. Recent evidence suggests that older adults name motor-related nouns (e.g., knife) more accurately than non-motor nouns (e.g., steak).
Yang Xiao, Yanping Dong
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

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