Results 101 to 110 of about 1,301,693 (307)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Genetic influences in different aspects of language development: The etiology of language skills in 4.5 year-old twins [PDF]

, 2005
The genetic and environmental etiologies of diverse aspects of language ability and disability, including articulation, phonology, grammar, vocabulary, and verbal memory, were investigated in a U.K.
Oliver, B., Plomin, Robert, Yulia Kovas (51504), Hayiou-Thomas, ME, Bonamy Oliver (16057061), Philip S Dale, Bishop, D.V.M., Dorothy V M Bishop (16159484), Hayiou-Thomas, Marianna E., Dale, P S, Philip S Dale (16159481), Robert Plomin (27675), Dale, Philip S., Bishop, D V M, Bonamy Oliver, Marianna E Hayiou-Thomas (16159472), Marianna E Hayiou-Thomas, Kovas, Yulia, Hayiou-Thomas, M.E., Hayiou-Thomas, M E, Dale, P.S., Dorothy V M Bishop, Plomin, R., Oliver, Bonamy R, Robert Plomin, Kovas, Y., Plomin, R, Kovas, Y, Bishop, Dorothy V., Yulia Kovas, Dale, PS, Bishop, DV, Oliver, B   +32 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

The relationship between procrastination and professional identity: the mediating role of self-efficacy and the moderating role of grades

Acta Psychologica
Procrastination is prevalent in higher education environments and can lead to numerous negative consequences. Previous studies have demonstrated that procrastination hurts professionalism, academic performance, and overall identity, but there is limited ...
Xiao Huang, Fairuz A'dilah Binti Rusdi
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Maturation Constraints on Language Development [PDF]

, 1988
Despite several decades of research and writing on the topic, serious differences of opinion persist as to the scope and source of maturational constraints on language development.
Long, Michael
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Caregiver-child neural synchrony: Magic, mirage, or developmental mechanism?

Developmental Cognitive Neuroscience
Young children transition in and out of synchronous states with their caregivers across physiology, behavior, and brain activity, but what do these synchronous periods mean? One body of two-brain studies using functional near-infrared spectroscopy (fNIRS)
Ellen C. Roche, Elizabeth Redcay, Rachel R. Romeo   +2 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source