Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
An Embodied question answering system for use in the treatment of eating disorders [PDF]
, 2008 This paper presents work in progress on implementing an embodied question answering system, Dr. Cecilia, in the form of a virtual caregiver, for use in the treatment of eating disorders.
Bergh, Cecilia +5 more
core +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Assessment and diagnosis of Developmental Language Disorder: The experiences of speech and language therapists [PDF]
, 2019 © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the ...
Bishop D. V. M. +7 more
core +2 more sources
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
The Efficacy of Telepractice in the Assessment and Treatment of Speech Disorders: A Systematic Review [PDF]
, 2019 Purpose: Children and adults with speech disorders face numerous barriers in accessing traditional face-to-face services with a speech-language pathologist. Telepractice may be a feasible solution. The aim of this systematic review was to investigate the
Cooley, Elizabeth +2 more
core +1 more source
Health Effects Associated With Electronic Cigarette Use: Automated Mining of Online Forums. [PDF]
, 2020 BACKGROUND:Our previous infodemiological study was performed by manually mining health-effect data associated with electronic cigarettes (ECs) from online forums.
Hristidis, Vagelis +3 more
core
Neural Correlates of Developmental Speech and Language Disorders: Evidence from Neuroimaging
Current Developmental Disorders Reports, 2014 Disorders of speech and language arise out of a complex interaction of genetic, environmental, and neural factors. Little is understood about the neural bases of these disorders.
F. Liégeois, Angela K Mayes, A. Morgan
semanticscholar +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Editorial Perspective: Speaking up for developmental language disorder – the top 10 priorities for research [PDF]
, 2022 Amit Kulkarni +14 more
openalex +1 more source