Results 61 to 70 of about 500,115 (309)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
SeBaSa, 2018 The Indonesian nation is currently in a language crisis. This linguistic crisis must be addressed wisely. The purpose of this study is to describe, design, and determine the effectiveness of the Indonesian language proficiency test application based on ...
Uki Hares Yulianti, Danang Wahyu Puspito
doaj +1 more source
Parents and children talk: the family dynamics of English language proficiency [PDF]
, 2004 This paper extends the analysis of the acquisition of destination language proficiency among immigrants by explicitly incorporating dynamics among family members— mother, father and children.
Chiswick, B.R., Lee, Y.L., Miller, P.W.
core
South African Journal of Education, 2013 We report on the relationships that exist between the critical thinking skills and the academic language proficiency ofa group of first-year prospective teachers at a South African university (n = 89).
M M (Mary) Grosser, Mirna Nel
doaj
EFL teacher burnout and self-assessed language proficiency: exploring possible relationships
Language Testing in Asia, 2019 Although teacher burnout has drawn the attention of many researchers, there is little empirical evidence for the contribution of non-native English language teachers’ language proficiency level to their experience of burnout.
Akram Nayernia, Zareh Babayan
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
A Preliminary Study on Why Second Language Learners Accept Ungrammatical Sentences: Its Theoretical Implications [PDF]
, 2018 Why do second language learners sometimes accept ungrammatical sentences in the target language? In the present study, we focus on Japanese-speaking learners of English as a Foreign Language (EFL) and investigate whether such “grammatical illusion ...
YAMADA, Toshiyuki
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
MOTIVATION AND LEARNING STYLE: DO THEY CORRELATE WITH LANGUAGE PROFICIENCY?
ELT Echo: The Journal of English Language Teaching in Foreign Language Context, 2019 This paper discusses the issues of motivational orientation, learner types and their relationship with English Language Proficiency among the students of semester one in the academic year 2018 / 2019 at the State Institute of Islamic Studies Syekh ...
Udin Kamiludin
doaj +1 more source