Results 31 to 40 of about 5,013,481 (277)

Family Language Policy in a Hakka Community in Sabah, Malaysia

Journal of Modern Languages, 2020
Hakka has been the lingua franca used among various Chinese groups in Sabah, Malaysia, since the 1950s. Economic development and de-emphasis on ethnic identity within Chinese communities throughout Malaysia is now forcing Sabah Hakkas to confront ...
Chih-I Liao
doaj   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

On the fringes of a diaspora : an appraisal of the literature on language diaspora and globalization in relation to a family of Tamil-speaking, Sri Lankan migrants to South Africa [PDF]

, 2012
Includes abstract.Includes bibliographical references.While the language attitudes and reported behaviours of migrants have long been of interest to linguists, educationalists and sociologists, increased levels of global mobility and technological ...
Govender, Shanali Candice
core   +1 more source

Another case of language death? The intergenerational transmission of Catalan in Alghero [PDF]

, 2012
PhDThis thesis is a study of linguistic contact in Alghero, a multilingual town on the north-west coast of Sardinia characterised by the presence of three main language varieties: Italian, Catalan, and Sardinian.
Chessa, Enrico
core   +2 more sources

Afrikaans as an index of identity among Western Cape Coloured communities

Stellenbosch Papers in Linguistics, 2011
In South Africa, reports on language shift have focused on instances of language shift from indigenous African languages to English. There is, however, also research that suggests that language shift is taking place from Afrikaans to English in the ...
Thutloa, Alfred Mautsane, Huddlestone, Kate   +1 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Ethnolinguistic vitality in Thulamela Local Municipality: A case of Xitsonga

Literator
The use and status of a language in a given speech community can reveal the prospects of its elevation or lack thereof. Furthermore, one can determine whether a language will be elevated or undermined in a community by exploring the perceptions of its ...
Rhulani S. Mashwele, Itani P. Mandende, Moffat Sebola   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Shift Still Happens: Spanish Language Maintenance in the Face of Growth and Change in the Western United States

Languages
The recent release of 2020 U.S. Census data reflects the continued growth of the Hispanic/Latino population over the last four decades. The Hispanic/Latino population has increased by a factor of 3.25 since 1980, with nearly one in five inhabitants of ...
Devin L. Jenkins
doaj   +1 more source