Results 31 to 40 of about 4,815,658 (272)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Family Language Policy in a Hakka Community in Sabah, Malaysia

open access: yesJournal of Modern Languages, 2020
Hakka has been the lingua franca used among various Chinese groups in Sabah, Malaysia, since the 1950s. Economic development and de-emphasis on ethnic identity within Chinese communities throughout Malaysia is now forcing Sabah Hakkas to confront ...
Chih-I Liao
doaj   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Afrikaans as an index of identity among Western Cape Coloured communities

open access: yesStellenbosch Papers in Linguistics, 2011
In South Africa, reports on language shift have focused on instances of language shift from indigenous African languages to English. There is, however, also research that suggests that language shift is taking place from Afrikaans to English in the ...
Thutloa, Alfred Mautsane   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Ethnolinguistic vitality in Thulamela Local Municipality: A case of Xitsonga

open access: yesLiterator
The use and status of a language in a given speech community can reveal the prospects of its elevation or lack thereof. Furthermore, one can determine whether a language will be elevated or undermined in a community by exploring the perceptions of its ...
Rhulani S. Mashwele   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Shift Still Happens: Spanish Language Maintenance in the Face of Growth and Change in the Western United States

open access: yesLanguages
The recent release of 2020 U.S. Census data reflects the continued growth of the Hispanic/Latino population over the last four decades. The Hispanic/Latino population has increased by a factor of 3.25 since 1980, with nearly one in five inhabitants of ...
Devin L. Jenkins
doaj   +1 more source

Religion, Language Maintenance, and Language Shift

open access: yes, 2023
Abstract This chapter explores the role of religious practice in the linguistic changes of Roman-period Gaul, both as a conservative factor in the retention of the local language, Gaulish, and as a Latinizing factor. Epigraphic sources show that domain-based choices linked to religious practices can be a crucial factor for evaluating ...
Olivier De Cazanove   +1 more
openaire   +1 more source

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