Results 51 to 60 of about 1,157,470 (266)
Introduction: The Hidden Adult in Children’s Literature
Jan Marten Ivo Klaver
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
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This study aimed to investigate the impact of utilizing ChatGPT on learner autonomy of third-year students of Faculty of English at the University of Danang – University of Foreign Language Studies (UD – UFLS).
Thuan Phung Tan +2 more
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Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
The farming ritual and the rice metaphor: how people of Kasepuhan Sinarresmi worship rice
Rice is the most important staple food in the world, and its management is therefore of vital importance. Rice management of the people of Kasepuhan Sinarresmi, Sukabumi Regency West Java, Indonesia is symbolized in cultural practices of farming.
Ekaning Krisnawati +4 more
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Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Nghiên cứu này mô tả quá trình thiết kế và đánh giá nền tảng học thành ngữ trực tuyến UTOPIDIOM bằng phương pháp nghiên cứu hỗn hợp tuần tự giải thích, kết hợp dữ liệu khảo sát định lượng với 100 người dùng và phỏng vấn bán cấu trúc với 10 sinh viên năm ...
Tran Ho Thanh Thao +4 more
doaj +1 more source
THE USE OF METALANGUAGE AMONG SECOND LANGUAGE LEARNERS TO MEDIATE L2 GRAMMAR LEARNING
Purpose – This study investigated the use of metalanguage as a mediational tool in understanding targeted grammatical concepts from the perspective of the Sociocultural approach (SCT) in learning a second language (L2).
Haliza Harun +3 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source

