Results 1 to 10 of about 18,195 (260)

Comparative Efficacy of Triple Versus Quadruple Therapy for the Eradication of <i>Helicobacter pylori</i> Infection in Asian Adults-A Systematic Review and Meta-Analysis. [PDF]

JGH Open
ABSTRACT Helicobacter pylori infection remains a major health issue in Asia due to its strong association with gastric ulcers and cancer. Rising antibiotic resistance has reduced the success of standard triple therapy, leading to broader use of bismuth‐based quadruple regimens.
Razzak A, Rahman N, Sarker N, Nil MS, Rahman MA, Mahmud MT.   +5 more
europepmc   +2 more sources

Collagenous colitis in patients treated for cancer: role of immune checkpoint inhibitors. Clinical, histological and immunological features in 15 cases. [PDF]

Histopathology
Immune checkpoint inhibitor‐associated collagenous colitis exhibits distinct histopathological and immunophenotypic features compared to idiopathic cases, including prominent sub‐epithelial macrophage accumulation and neutrophilic cryptitis. These findings underscore the pathogenic impact of PD1/PD‐L1 axis blockade on colonic mucosa and expand the ...
Bani MA, Dartigues P, Soufan R, Cosconea S, Ducreux M, Robert C, Guenzi E, Danlos FX, Marabelle A, Carbonnel F, Scoazec JY.   +10 more
europepmc   +2 more sources

Pharmacokinetic Profiles of Lansoprazole in Patients With Morbid Obesity Post‐Roux‐en‐Y Gastric Bypass Surgery [PDF]

Clinical and Translational Science
Data on the effects of Roux‐en‐Y gastric bypass (RYGB) surgery on lansoprazole pharmacokinetics in morbidly obese patients are limited. This study aimed to evaluate the impact of RYGB surgery on the pharmacokinetic profile of lansoprazole in Thai ...
Suthep Udomsawaengsup, Sathienrapong Chantawibul, Naranon Boonyuen, Sarunnuch Panyavorakhunchai, Pattharasai Kachornvitaya, Wasu Wisanuyothin, Pittawat Somvanapanich, Warittha Lertwatthiphong, Napatsanan Tanathitiphuwarat, Pajaree Chariyavilaskul   +9 more
doaj   +2 more sources

Lansoprazole protects hepatic cells against cisplatin-induced oxidative stress through the p38 MAPK/ARE/Nrf2 pathway

PLoS ONE, 2023
Lansoprazole, a proton pump inhibitor, can exert antioxidant effects through the induction of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, independently of the inhibition of acid secretion in the gastrointestinal tract.
Naoko Yamagishi, Yuta Yamamoto, Toshio Nishi, Takao Ito, Yoshimitsu Kanai   +4 more
doaj   +3 more sources

Omeprazole and lansoprazole enantiomers induce CYP3A4 in human hepatocytes and cell lines via glucocorticoid receptor and pregnane X receptor axis. [PDF]

PLoS ONE, 2014
Benzimidazole drugs lansoprazole and omeprazole are used for treatment of various gastrointestinal pathologies. Both compounds cause drug-drug interactions because they activate aryl hydrocarbon receptor and induce CYP1A genes.
Aneta Novotna, Zdenek Dvorak
doaj   +1 more source

The effectiveness and cost of lansoprazole and pantoprazole for stress ulcer prophylaxis in intensive care unit [PDF]

Pharmaciana, 2021
The incidence of bleeding is increased in high risk patients with critical conditions in Intensive Care Unit (ICU). Appropriate prophylaxis medicine is necessary to reduce the incidence of stress ulcer bleeding during hospitalization in ICU which further
Mega Octavia, Zullies Ikawati, Tri Murti Andayani   +2 more
doaj   +1 more source

Efficacy of soluble lansoprazole-impregnated beta-tricalcium phosphate for bone regeneration

Scientific Reports, 2022
The proton pump inhibitor lansoprazole has been previously identified to upregulate the expression and transcriptional activity of runt-related transcription factor 2 (Runx2) that promotes lineage commitment and differentiation of osteoprogenitor cells ...
Kenichi Mishima, Yuka Tsukagoshi Okabe, Masaaki Mizuno, Kinji Ohno, Hiroshi Kitoh, Shiro Imagama   +5 more
doaj   +1 more source

Lansoprazole – Induce Black Hairy Tongue- A Case Report

Nepal Journal of Dermatology, Venereology & Leprology, 2017
Lansoprazole induced black hairy tongue has been rarely reported. The purpose of this paper is to report a case of lansoprazole induce black hairy tongue and review the literature.
Eliz Aryal, M Rajbhandari, Sabina Bhattarai   +2 more
doaj   +3 more sources

Lansoprazole-induced hypomagnesaemia [PDF]

BMJ Case Reports, 2014
The introduction of proton pump inhibitors (PPIs) in the late 1980s optimised the medical treatment of acid-related disorders. They are potent medications and have a good safety profile. However, long-term therapy with PPIs may carry undesired side effects, one of which is hypomagnesaemia. This entity is likely to be under-reported.
Lukasz Zbigniew Krupa, Ian W Fellows
openaire   +3 more sources

Association between clinical use of lansoprazole and the risk of type 2 diabetes mellitus: a pharmacoepidemiological cohort study

Diabetology & Metabolic Syndrome, 2023
Background Proton pump inhibitors (PPIs) are common and widely used for gastrointestinal-related disorders. Lansoprazole is one of PPIs with potential benefits of anti-inflammation, reduced oxidative stress, and anti-diabetes.
Ming-Hsun Lin, Wen‐Tung Wu, Yong-Chen Chen, Tsung-Kun Lin, Yu‐Ching Chou, Chien‐An Sun   +5 more
doaj   +1 more source