Results 21 to 30 of about 10,268 (212)

Electrochemical behavior of lansoprazole at a multiwalled carbon nanotubes-ionic liquid modified glassy carbon electrode and its electrochemical determination [PDF]

Journal of the Serbian Chemical Society, 2014
The electrochemical behavior of lansoprazole (LNS) has been investigated at a glassy carbon electrode (GCE) and the electrode modified by a gel containing multiwalled carbon nanotubes (MWCNTs) and an room-temperature ionic liquid (RTIL) of 1 ...
Liu Li-Hong, You Wei, Zhan Xue-Mei, Gao Zuo-Ning   +3 more
doaj   +1 more source

Gastric Ulcer Prevention by Lansoprazole [PDF]

Gastroenterology Pancreatology and Hepatobilary Disorders, 2019
The objective of the current investigation is to formulate ethyl cellulose and hydroxypropyle methyle cellulose based sustained release microspheres, containing lansoprazole as model drugs. lansoprazole is type II anti-ulcer agent when administered shows synergetic effect in their action.
Stalin reddy Challa, Prasad Garrepally
openaire   +1 more source

Lansoprazole Upregulates Polyubiquitination of the TNF Receptor-Associated Factor 6 and Facilitates Runx2-mediated Osteoblastogenesis

EBioMedicine, 2015
The transcription factor, runt-related transcription factor 2 (Runx2), plays a pivotal role in the differentiation of the mesenchymal stem cells to the osteochondroblast lineages.
Kenichi Mishima, Hiroshi Kitoh, Bisei Ohkawara, Tatsuya Okuno, Mikako Ito, Akio Masuda, Naoki Ishiguro, Kinji Ohno   +7 more
doaj   +1 more source

Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort.

PLoS Medicine, 2017
BackgroundRecent in vitro and animal studies have found the proton pump inhibitor (PPI) lansoprazole to be highly active against Mycobacterium tuberculosis. Omeprazole and pantoprazole have no activity.
Tom A Yates, Laurie A Tomlinson, Krishnan Bhaskaran, Sinead Langan, Sara Thomas, Liam Smeeth, Ian J Douglas   +6 more
doaj   +1 more source

Lansoprazole Alone or in Combination With Gefitinib Shows Antitumor Activity Against Non-small Cell Lung Cancer A549 Cells in vitro and in vivo

Frontiers in Cell and Developmental Biology, 2021
Lansoprazole (Lpz) is an FDA-approved proton pump inhibitor (PPI) drug for the therapy of acid-related diseases. Aiming to explore the new application of old drugs, we recently investigated the antitumor effect of Lpz.
Xiaoxia Zhao, Ning Zhang, Yingying Huang, Xiaojing Dou, Xiaolin Peng, Wei Wang, Zhe Zhang, Ran Wang, Yuling Qiu, Meihua Jin, Dexin Kong, Dexin Kong   +11 more
doaj   +1 more source

Detection, Isolation and Characterization of Principal Synthetic Route Indicative Impurity in Lansoprazole

E-Journal of Chemistry, 2010
An unknown impurity in lansoprazole (2-[[[3-methyl-4-(2, 2, 2-trifluoroethoxy)-2-pyridyl] methyl] sulfinyl] benzimidazole) was detected by HPLC and was identified as des-(trifluoroethoxy) lansoprazole, an principal synthetic route indicative impurity of ...
K. S. V Srinivas, K. Mukkanti, R. Buchi Reddy, P. Srinivasulu   +3 more
doaj   +1 more source

The proton-pump inhibitor lansoprazole enhances amyloid beta production.

PLoS ONE, 2013
A key event in the pathogenesis of Alzheimer's disease (AD) is the accumulation of amyloid-β (Aβ) species in the brain, derived from the sequential cleavage of the amyloid precursor protein (APP) by β- and γ-secretases.
Nahuai Badiola, Victor Alcalde, Albert Pujol, Lisa-Marie Münter, Gerd Multhaup, Alberto Lleó, Mireia Coma, Montserrat Soler-López, Patrick Aloy   +8 more
doaj   +1 more source

Comparative analysis of the effect of PO administered acid suppressants on gastric pH in healthy cats

Journal of Veterinary Internal Medicine, 2020
Background Proton pump inhibitors (PPIs) are among the most commonly prescribed medications for esophagitis and upper gastrointestinal erosion and ulceration in cats.
Phillip Ryan, Adesola Odunayo, Josh Price, Silke Hecht, Shanna Hillsman, Gina Galyon, Joerg Steiner, M. Katherine Tolbert   +7 more
doaj   +1 more source

Pharmacokinetic Study and Incurred Sample Stability of Esomeprazole in Dried Blood Spot Sample Using High Performance Liquid Chromatography-Photodiode Array

Indonesian Journal of Chemistry, 2020
In the past years, Esomeprazole (EMP) was analyzed in human plasma samples, which still has stability issues; thus, the new biosampling technique known as Dried Blood Spot (DBS) might solve the issue.
Yahdiana Harahap, Anja Tamabri, Vicha Vicha, Herman Suryadi, Sunarsih Sunarsih, Callista Andinie Mulyadi   +5 more
doaj   +1 more source

Pretreatment of Garlic Oil Extracts Hampers Epithelial Damage in Cell Culture Model of Peptic Ulcer Disease

Medicina, 2022
Background and Objectives: Peptic ulcer disease is a chronic disease affecting up to 10% of the world’s population. Proton pump inhibitors, such as lansoprazole are the gold standard in the treatment of ulcer disease.
Lucija Kuna, Milorad Zjalic, Tomislav Kizivat, Hrvoje Roguljic, Vjera Nincevic, Tea Omanovic Kolaric, Catherine H. Wu, Aleksandar Vcev, Martina Smolic, Robert Smolic   +9 more
doaj   +1 more source