Results 1 to 10 of about 16,188 (197)
Vonoprazan attenuates proteinuria in diabetic kidney disease through potential direct renal mechanism [PDF]
Scientific ReportsOur study investigates the effect of vonoprazan on albuminuria in diabetic kidney disease (DKD) patients compared to lansoprazole through a randomized controlled trial. Participants were randomized to receive either lansoprazole 30 mg or vonoprazan 20 mg.
Rabab Mahmoud Ahmed +2 more
doaj +2 more sources
EBioMedicine, 2015 The transcription factor, runt-related transcription factor 2 (Runx2), plays a pivotal role in the differentiation of the mesenchymal stem cells to the osteochondroblast lineages.
Kenichi MISHIMA +2 more
exaly +3 more sources
PLoS ONE, 2023 Lansoprazole, a proton pump inhibitor, can exert antioxidant effects through the induction of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, independently of the inhibition of acid secretion in the gastrointestinal tract.
Naoko Yamagishi +4 more
doaj +3 more sources
Omeprazole and lansoprazole enantiomers induce CYP3A4 in human hepatocytes and cell lines via glucocorticoid receptor and pregnane X receptor axis. [PDF]
PLoS ONE, 2014 Benzimidazole drugs lansoprazole and omeprazole are used for treatment of various gastrointestinal pathologies. Both compounds cause drug-drug interactions because they activate aryl hydrocarbon receptor and induce CYP1A genes.
Aneta Novotna, Zdenek Dvorak
doaj +1 more source
The effectiveness and cost of lansoprazole and pantoprazole for stress ulcer prophylaxis in intensive care unit [PDF]
Pharmaciana, 2021 The incidence of bleeding is increased in high risk patients with critical conditions in Intensive Care Unit (ICU). Appropriate prophylaxis medicine is necessary to reduce the incidence of stress ulcer bleeding during hospitalization in ICU which further
Mega Octavia +2 more
doaj +1 more source
Efficacy of soluble lansoprazole-impregnated beta-tricalcium phosphate for bone regeneration
Scientific Reports, 2022 The proton pump inhibitor lansoprazole has been previously identified to upregulate the expression and transcriptional activity of runt-related transcription factor 2 (Runx2) that promotes lineage commitment and differentiation of osteoprogenitor cells ...
Kenichi Mishima +5 more
doaj +1 more source
Lansoprazole – Induce Black Hairy Tongue- A Case Report
Nepal Journal of Dermatology, Venereology & Leprology, 2017 Lansoprazole induced black hairy tongue has been rarely reported. The purpose of this paper is to report a case of lansoprazole induce black hairy tongue and review the literature.
Eliz Aryal +2 more
doaj +3 more sources
Diabetology & Metabolic Syndrome, 2023 Background Proton pump inhibitors (PPIs) are common and widely used for gastrointestinal-related disorders. Lansoprazole is one of PPIs with potential benefits of anti-inflammation, reduced oxidative stress, and anti-diabetes.
Ming-Hsun Lin +5 more
doaj +1 more source
Biosensors, 2023 The efficacies and toxicities of chiral drug enantiomers are often dissimilar, necessitating chiral recognition methods. Herein, a polylysine–phenylalanine complex framework was used to prepare molecularly imprinted polymers (MIPs) as sensors with ...
Lianming Zhang +5 more
doaj +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2015 The aim of this study was to evaluate the effects of caffeine, tea polyphenol and daidzein on the pharmacokinetics of lansoprazole and its metabolites. Rats were intragastrically administered caffeine (30 mg·kg-1, once per day), tea polyphenol (400 mg·kg-
Tao Wu +5 more
doaj +1 more source