Results 91 to 100 of about 14,107,293 (207)

Pre-assessment on the loss and impact caused by large-scale flood disasters

, 2006
Through intensive studies, we have established an index system for evaluating the loss and impact caused by large-scale flood disasters, and constructed a methodological system for pre-assessing the loss and impact caused by large-scale flood disasters ...
Kang, XW, Inst Sci & Tech Informat China, Beijing 100038, Peoples R China, Wu Shaohong, Liu Ziqiang, Zhao Ruifeng, Yang Qinye, Ma Xin, Kang Xiangwu, Dai Erfu, Yang Peiguo   +8 more
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

From purpose in life to global engagement: the mediating role of global mindedness in adolescence

Frontiers in Education
IntroductionAdolescents’ purpose in life is a vital psychosocial resource associated with social contribution. This study investigates how purpose in life promotes engagement with global issues and whether this relationship is mediated by global ...
Yeonwho Kim, Hayeon Kim
doaj   +1 more source

Large scale MTConnect data collection

, 2019
Data collection is the first stage of data lifecycle to drive manufacturing activities such as monitoring, prediction and optimization. Data collection at shop floor is more complex since it is affected by both the physical and cyber worlds.
Chan, Ka C., Ka C. Chan, Sami Kara, Cui, Yesheng, Kara, Sami, Yesheng Cui   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The impact of food poverty on educational achievement: a New Zealand case study in global context

Frontiers in Education
Hunger negatively impacts a student’s ability to engage and learn at school. Rising food poverty among school students across the globe is increasingly recognized as a critical factor impacting educational achievement.
Pippa McKelvie Sebileau, Pippa McKelvie Sebileau, Boyd Swinburn, Boyd Swinburn, Jamie de Seymour   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

二階段分層叢集抽樣的設計效應估計：以TIMSS 2007調查研究為例 An Estimation of the Design Effect for the Two-Stage Stratified Cluster Sampling Desig

Journal of Research in Education Sciences, 2011
大型調查研究常採用多階段分層叢集抽樣，檢視臺灣學生歷年來參與TIMSS 研究的結果顯示，其平均表現之標準誤常較他國稍大。應TIMSS 專責抽樣之單位要求，本研究旨在推導設計二階段分層叢集抽樣時即可預估標準誤的公式，以利選擇較佳分層架構，達減少標準誤的目標，並進行三個分析檢查其有效性。分析一將30 個參與TIMSS 2007 的國家資料，用該公式與《TIMSS 技術手冊》建議之刀切重複取樣法，分別估算各國學生平均科學成績之標準誤，發現兩者之線性相關達 .98。分析二以29 個連續參加TIMSS ...
任宗浩 Tsung-Hau Jen, 譚克平 Hak-Ping Tam, 張立民 Margaret Wu   +2 more
doaj   +1 more source

Cloud cover : monitoring large-scale clouds with Varanus [PDF]

, 2015
This research was supported by a Royal Society Industry Fellowship and an Amazon Web Services (AWS) grant.Cloud computing has quickly become the de facto means to deploy large scale systems in a robust and cost effective manner.
Barker, Adam David, Ward, Jonathan Stuart, Jonathan Stuart Ward, Adam Barker   +3 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source