Large-scale data analysis for robotic yeast one-hybrid platforms and multi-disciplinary studies using GateMultiplex. [PDF]
BMC Biol, 2021 Tsai NC +13 more
europepmc +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
How recreational marathon runners hit the wall: A large-scale data analysis of late-race pacing collapse in the marathon. [PDF]
PLoS One, 2021 Smyth B.
europepmc +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Analysis input data and scripts for, "Large-scale reference-free analysis of flavivirus sequences in Aedes aegypti whole genome DNA sequencing data"
Campino, Susana +3 more
core +1 more source
Minimizing acquisition-related radiomics variability by image resampling and batch effect correction to allow for large-scale data analysis. [PDF]
Eur Radiol, 2021 Ligero M +14 more
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A graph-powered large-scale fraud detection system
Graph-powered fraud detection is a common issue in various areas, such as e-commerce, banking, insurance and social networks, where data can be naturally formulated as graph structure.
Jin, Yilun +6 more
core +1 more source
Understanding the spatial and temporal impact of global events through large-scale social media data
EPJ Data ScienceLarge-scale urban social media data can provide substantial insights into the real-time development of cities around the globe, illuminating phenomena such as gentrification, urban decay, and resilience to major adverse events.
Ann-Kathrin Meyer, Tobias Brandt
doaj +1 more source
Patient characteristics, treatment patterns, and outcomes of hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer patients prescribed cyclin-dependent kinase 4 and 6 inhibitors: large-scale data analysis using a Japanese claims database. [PDF]
Breast Cancer Res Treat, 2023 Kawai M +8 more
europepmc +1 more source