Results 101 to 110 of about 11,465 (256)

DarkAI: Reconstructing the Density, Velocity, and Tidal Fields of Dark Matter from a DESI-like Bright Galaxy Sample

The Astrophysical Journal Supplement Series
Reconstructing the mass density, velocity, and tidal (MTV) fields of dark matter from galaxy surveys is essential for advancing our understanding of the large-scale structure of the Universe.
Feng Shi, Zitong Wang, Xiaohu Yang, Yizhou Gu, Chengliang Wei, Ming Li, Jiaxin Han, Zhejie Ding, Huiyuan Wang, Youcai Zhang, Wensheng Hong, Yirong Wang, Xiao-dong Li   +12 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Orthogonal Alignment of Galaxy Group Angular Momentum with Cosmic Filament Spines: An Observational Study

The Astrophysical Journal Letters
We investigated the alignment between the angular momenta of galaxy groups and the spines of their associated cosmic filaments. Our results demonstrate a significant tendency for these two orientations to be perpendicular, indicating that the rotation of
Yu Rong, Peng Wang, Xiao-xiao Tang
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Recovering Cosmic Structure with a Simple Physical Constraint

The Astrophysical Journal
Radio observation of the large-scale structure (LSS) of our Universe faces major challenges from foreground contamination, which is many orders of magnitude stronger than the cosmic signal.
Tian-Cheng Luan, Xin Wang, Jiacheng Ding, Qian Li, Xiao-Dong Li, Weishan Zhu   +5 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Enhancing Morphological Measurements of the Cosmic Web with Delaunay Tessellation Field Estimation

The Astrophysical Journal Supplement Series
The density fields constructed by traditional mass assignment methods are susceptible to irritating discreteness, which hinders morphological measurements of cosmic large-scale structure (LSS) through Minkowski functionals (MFs). To alleviate this issue,
Yu Liu, Yu Yu, Pengjie Zhang, Hao-Ran Yu
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Correlation-based Beam Calibration of 21 cm Intensity Mapping

The Astrophysical Journal Supplement Series
Foreground removal presents a significant obstacle in both current and forthcoming intensity-mapping surveys. While numerous techniques have been developed that show promise in simulated data sets, their efficacy often diminishes when they are applied to
Jiacheng Ding, Xin Wang, Ue-Li Pen, Xiao-Dong Li   +3 more
doaj   +1 more source