Results 111 to 120 of about 179,347,395 (254)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Monopole Fluctuations in Galaxy Surveys
The Astrophysical Journal LettersGalaxy clustering provides a powerful way to probe cosmology. This requires understanding of the background mean density of galaxy samples, which is estimated from the survey itself by averaging the observed galaxy number density over the angular ...
Jaiyul Yoo, Daniel Eisenstein
doaj +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
The Astrophysical JournalWe apply an extended Alcock–Paczyński (AP) test to the Sloan Digital Sky Survey data to constrain the dark energy models with the Chevallier–Polarski–Linder (CPL) parametrization of the dark energy equation of state.
Fuyu Dong, Changbom Park
doaj +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Cosmological Prediction from the Joint Observation of MeerKAT and CSST at z = 0.4 – 1.2
The Astrophysical JournalCross-correlating neutral hydrogen (H i ) 21 cm intensity mapping with galaxy surveys provides an effective probe of astrophysical and cosmological information.
Yu-Er Jiang +12 more
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
The Astrophysical Journal LettersWe present an observational study of the kinematic coherence between satellite orbital planes and the cosmic web. Using the SDSS DR12 galaxy sample combined with the Bisous filament catalogue, we investigate whether the orbital motion of satellites ...
Peng Wang +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
The Ophiuchus Cluster and a Large-Scale Structure toward the Galactic Centre
, 2004 The Ophiuchus Cluster is one of the most luminous X-ray clusters in the local Universe, and may be a key cluster for the local large-scale structure. Our preliminary redshift-survey with FLAIR and 6dF for the cluster shows the following: 1) a velocity ...
Wakamatsu, K +6 more
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