Results 81 to 90 of about 1,581 (277)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 2011 This paper continues the study of the Ramsey-like large cardinals introduced in [5] and [14]. Ramsey-like cardinals are defined by generalizing the characterization of Ramsey cardinals via the existence of elementary embeddings. Ultrafilters derived from
P. D. Welch, Victoria Gitman
core +1 more source
Determinacy and Large Cardinals
, 2023 The study of inner models was initiated by Gödel's analysis of the constructible universe. Later, the study of canonical inner models with large cardinals, e.g., measurable cardinals, strong cardinals or Woodin cardinals, was pioneered by Jensen, Mitchell, Steel, and others.
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Large cardinals and definable well-orderings of the universe
, 2007 We use a reverse Easton forcing iteration to obtain a universe with a definable well-ordering, while preserving the GCH and proper classes of a variety of very large cardinals. This is achieved by using the principle at a proper class of cardinals k.
Brooke-Taylor, AD
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Large cardinals and gap-1 morasses
, 2009 We present a new partial order for directly forcing morasses to exist that enjoys a significant homogeneity property. We then use this forcing in a reverse Easton iteration to obtain an extension universe with morasses at every regular uncountable ...
Sy-David Friedman +3 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Cardinals Beyond Choice and the HOD-Dichotomy [PDF]
, 2020 Treballs Finals del Màster de Lògica Pura i Aplicada, Facultat de Filosofia, Universitat de Barcelona. Curs: 2019-2020. Tutor: Joan BagariaIn the 2019 paper "Large Cardinals Beyond Choice" [1], Bagaria, Koellner and Woodin apply the large cardinal ...
Spoerl, John
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source