Results 101 to 110 of about 1,290,183 (324)

Supernova and neutron star limits on large extra dimensions reexamined [PDF]

open access: yes, 2003
In theories with large extra dimensions, supernova ~SN! cores are powerful sources of Kaluza-Klein ~KK! gravitons. A large fraction of these massive particles are gravitationally retained by the newly born neutron star ~NS!. The subsequent slow KK decays
S. Hannestad, G. Raffelt
semanticscholar   +1 more source

A new mechanism for symmetry breaking from nilmanifolds

open access: yesJournal of High Energy Physics, 2020
We present a method to obtain a scalar potential at tree level from a pure gauge theory on nilmanifolds, a class of negatively-curved compact spaces, and discuss the spontaneous symmetry breaking mechanism induced in the residual Minkowski space after ...
David Andriot   +4 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Interpreting the 3 TeV WH resonance as a W′ boson

open access: yesJournal of High Energy Physics, 2017
Motivated by a local 3.2 − 3.4 sigma resonance in WH and ZH in the ATLAS Run 2 data, we attempt to interpret the excess in terms of a W′ boson in a SU(2)1 × SU(2)2×U(1)X model. We stretch the deviation from the alignment limit of the Equivalence Theorem,
Kingman Cheung   +3 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Gravitational resonances in mimetic thick branes

open access: yesJournal of High Energy Physics, 2019
In this work, we investigate gravitational resonances in both single and double mimetic thick branes, which can provide a new way to detect the extra dimension. For the single brane model, we apply the relative probability proposed in [Phys. Rev.
Yi Zhong   +3 more
doaj   +1 more source

Explaining Atomki anomaly and muon g − 2 in U(1) X extended flavour violating two Higgs doublet model

open access: yesJournal of High Energy Physics, 2021
We investigate a two Higgs doublet model with extra flavour depending U(1) X gauge symmetry where Z′ boson interactions can explain the Atomki anomaly by choosing appropriate charge assignment for the SM fermions.
Takaaki Nomura, Prasenjit Sanyal
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong   +7 more
wiley   +1 more source

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