Results 101 to 110 of about 16,605,417 (300)

Uncertainty quantification by large language models

Machine Learning with Applications
As reasoning capabilities of large language models (LLMs) continue to advance, they are being integrated into increasingly complex scientific workflows, with the goal of developing agents capable of generating evidence-based explanations and testing ...
Dorianis M. Perez, Bryan E. Kaiser, Ismael Boureima   +2 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Evaluating Large Language Models for Burning Mouth Syndrome Diagnosis [PDF]

Takayuki Suga,1 Osamu Uehara,2 Yoshihiro Abiko,3 Akira Toyofuku1 1Department of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan; 2Division of Disease Control and Molecular Epidemiology ...
Suga T, Toyofuku A, Uehara O, Abiko Y
core  

Can Large Language Models Predict Antimicrobial Peptide Activity and Toxicity? [PDF]

Antimicrobial peptides (AMPs) are naturally occurring or designed peptides up to a few tens of amino acids which may help address the antimicrobial resistance crisis.
Markus, Orsi, Jean-Louis, Reymond
core   +1 more source

Large Language Models for Manufacturing

CoRR
The rapid advances in Large Language Models (LLMs) have the potential to transform manufacturing industry, offering new opportunities to optimize processes, improve efficiency, and drive innovation. This paper provides a comprehensive exploration of the integration of LLMs into the manufacturing domain, focusing on their potential to automate and ...
Yiwei Li 0002, Huaqin Zhao, Hanqi Jiang, Yi Pan 0001, Zhengliang Liu, Zihao Wu 0001, Peng Shu, Jie Tian, Tianze Yang, Shaochen Xu, Yanjun Lyu, Parker Blenk, Jacob Pence, Jason Rupram, Eliza Banu, Ninghao Liu 0001, Linbing Wang, Wen-Zhan Song 0001, Xiaoming Zhai, Kenan Song, Dajiang Zhu, Beiwen Li, Xianqiao Wang, Tianming Liu 0001   +23 more
openaire   +3 more sources

Ensemble Large Language Models: A Survey

Information
Large language models (LLMs) have transformed the field of natural language processing (NLP), achieving state-of-the-art performance in tasks such as translation, summarization, and reasoning.
Ibomoiye Domor Mienye, Theo G. Swart
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Large language models in critical care

Journal of Intensive Medicine
The advent of chat generative pre-trained transformer (ChatGPT) and large language models (LLMs) has revolutionized natural language processing (NLP).
Laurens A. Biesheuvel, Jessica D. Workum, Merijn Reuland, Michel E. van Genderen, Patrick Thoral, Dave Dongelmans, Paul Elbers   +6 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Industrial applications of large language models

Scientific Reports
Large language models (LLMs) are artificial intelligence (AI) based computational models designed to understand and generate human like text. With billions of training parameters, LLMs excel in identifying intricate language patterns, enabling remarkable
Mubashar Raza, Zarmina Jahangir, Muhammad Bilal Riaz, Muhammad Jasim Saeed, Muhammad Awais Sattar   +4 more
doaj   +1 more source