Results 111 to 120 of about 515,234 (309)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Human languaging and large language models
AI & SOCIETYAbstract This paper explores the interplay between human languaging and AI-powered language models from the view of the distributed language perspective (DLP). According to this perspective, human linguistic activity can be described as ongoing, heterogenous activity, thus making proponents of DLP prefer the term ‘languaging’ to that ...
openaire +2 more sources
Large language models robustness against perturbation
Scientific ReportsLarge Language Models (LLMs) have demonstrated impressive performance across various natural language processing (NLP) tasks, including text summarization, classification, and generation.
Saeed S. Alahmari +3 more
doaj +1 more source
Large Language Models: А Socio-Philosophical Essay
Галактика медиа: журнал медиа исследованийNeural networks have filled the information space. On the one hand, this indicates the scientific and technological movement of contemporary society (perhaps, AGI is already waiting for us outside the door). On the other hand, in everyday discourse there
Regina V. Penner
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Entropy in Large Language Models
CoRRIn this study, the output of large language models (LLM) is considered an information source generating an unlimited sequence of symbols drawn from a finite alphabet. Given the probabilistic nature of modern LLMs, we assume a probabilistic model for these LLMs, following a constant random distribution and the source itself thus being stationary.
openaire +2 more sources
Can Large Language Models Predict Antimicrobial Peptide Activity and Toxicity?
Antimicrobial peptides (AMPs) are naturally occurring or designed peptides up to a few tens of amino acids which may help address the antimicrobial resistance crisis.
Markus, Orsi, Jean-Louis, Reymond
core +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source