Results 111 to 120 of about 16,605,417 (300)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Leveraging large language models for medical text classification: a hospital readmission prediction case

In recent years, the intersection of natural language processing (NLP) and healthcare informatics has witnessed a revolutionary transformation. One of the most groundbreaking developments in this realm is the advent of large language models (LLM), which ...
Nazyrova, Nodira, Chahed, Salma, Chausalet, Thierry, Dwek, Miriam   +3 more
core   +1 more source

Leveraging Large Pre-trained Multilingual Models for High-Quality Speech-to-Text Translation on Industry Scenarios

International audienceSpeech-to-Text Translation (S2TT) involves converting spoken language from a source language directly into text in a target language.
Avila, Marko, Crego, Josep
core   +1 more source

Large scale paired antibody language models.

PLoS Computational Biology
Antibodies are proteins produced by the immune system that can identify and neutralise a wide variety of antigens with high specificity and affinity, and constitute the most successful class of biotherapeutics.
Henry Kenlay, Frédéric A Dreyer, Aleksandr Kovaltsuk, Dom Miketa, Douglas Pires, Charlotte M Deane   +5 more
doaj   +1 more source

Large Language Models: А Socio-Philosophical Essay

Галактика медиа: журнал медиа исследований
Neural networks have filled the information space. On the one hand, this indicates the scientific and technological movement of contemporary society (perhaps, AGI is already waiting for us outside the door). On the other hand, in everyday discourse there
Regina V. Penner
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Fine-tuning Large Language Models for Chemical Text Mining [PDF]

Extracting knowledge from complex and diverse chemical texts is a pivotal task for both experimental and computational chemists. The task is still considered to be extremely challenging due to the complexity of the chemical language and scientific ...
Yitian, Wang, Duanhua, Cao, Runze, Zhang, Qinggong, Wang, Buying, Niu, Mingan, Chen, Ziming, Huang, Lehan, Zhang, Xutong, Li, Qian, Shi, Shengkun, Ni, Zunyun, Fu, Jiacheng, Xiong, Mingyue, Zheng, Zhaoping, Xiong, Xiangtai, Kong, Wei, Zhang   +16 more
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Eliciting Metaknowledge in Large Language Models

Advances in Natural Language Processing led to the introduction of Large Language Models (LLMs), that have been found endowed of enriched capabilities and improved performance results when increased in size.
Misael Mongiovì, Antonio Lieto, Luana Bulla, Carmelo Fabio Longo   +3 more
core  

Entropy in Large Language Models

CoRR
In this study, the output of large language models (LLM) is considered an information source generating an unlimited sequence of symbols drawn from a finite alphabet. Given the probabilistic nature of modern LLMs, we assume a probabilistic model for these LLMs, following a constant random distribution and the source itself thus being stationary.
openaire   +3 more sources