Results 31 to 40 of about 670,959 (215)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Modelling and Simulation of a Rectangular Large Mode Area Photonic Crystal Fiber [PDF]

open access: yesEPJ Web of Conferences
This work presents a rectangular large core area (R-LCA) PCF with a cladding diameter of 125 µm, a pitch of 9 µm, and a hole diameter of 8 µm. The guided modes were obtained through numerical simulations using COMSOL Multiphysics.
Rúben Alves Mário   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Stabilized Large Mode Area in Tapered Photonic Crystal Fiber for Stable Coupling

open access: yesIEEE Photonics Journal, 2012
A rigorous modal solution approach based on the numerically efficient finite element method (FEM) has been used to design a tapered photonic crystal fiber with a large mode area that could be efficiently coupled to an optical fiber.
M. Uthman   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Large mode area waveguide based high-energy passively Q-switched laser in silicon photonics [PDF]

open access: yesEPJ Web of Conferences
We demonstrate high energy Q-switched pulse generation with the help of a large mode area gain waveguide in a silicon photonics device. Output pulse energy >150 nJ and laser slope efficiency of 40% is shown.
Singh Neetesh   +15 more
doaj   +1 more source

High-Order Modes Suppression in All-Glass Large-Mode Area Rare-Earth Doped Optical Fibers with Modified Cladding

open access: yesPhotonics, 2022
In the present work we have developed and realized a high core-to-cladding diameters ratio active optical fibers operated in a single-mode regime due to specially designed structure containing boron-doped and fluorine-doped rods.
Svetlana S. Aleshkina   +7 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Black Phosphorus Q-Switched Large-Mode-Area Tm-Doped Fiber Laser

open access: yesInternational Journal of Optics, 2018
We report on a passively Q-switched fiber laser with black phosphorus as saturable absorber. By employing the sol-gel fabricated large-mode-area Tm-doped fiber as gain medium, a high-energy Q-switched fiber laser has been demonstrated which delivers the ...
Yan Ren   +9 more
doaj   +1 more source

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